Purpose
To report the clinical and histologic features of cystic benign melanosis.
Methods
This case series reports on the clinical and histopathologic features of three patients with enlarging cystic, brown pigmented conjunctival lesions.
Results
Slit lamp exam showed cystic melanotic lesions of bulbar conjunctiva. Histopathologic examination of the biopsy specimens showed epithelial lined cysts in the substantia propria, goblet cells, and secondary pigmentation of basilar keratinocytes.
Conclusions
Cystic benign melanosis, a unique conjunctival lesion, should be differentiated from cystic nevus and primary acquired melanosis (PAM).
Purpose
To report a patient with a tumor-like corneal keloid.
Methods
Retrospective review of clinical features and histopathologic findings.
Results
A 68-year-old woman with a remote history of an orbital tumor treated with radiation developed a corneal tumor. A biopsy of the tumor showed fibrocellular tissue and her blind, painful eye was enucleated. Pathologic findings in the enucleated eye showed that the corneal mass was consistent with a large keloid.
Conclusions
A corneal keloid may clinically appear as a large corneal tumor.
Purpose
To describe a rare case of primary conjunctival clear cell carcinoma.
Methods
The clinical history and pathologic findings were reviewed.
Results
An 82-year-old white man presented with a lesion on his right conjunctiva for 8 months. An excisional biopsy was performed with wide margins and mitomycin C. Pathologic examination showed a papillary clear cell carcinoma of the conjunctiva. The patient has been followed for 6 months without recurrence.
Conclusions
Primary clear cell carcinoma, a variant of squamous cell carcinoma, can occur in the conjunctiva.