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Filter Results:

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  • 2012 (1)
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Author

  • Justice, Amy C. (3)
  • Rimland, David (3)
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  • Journal of Acquired Immune Deficiency Syndromes
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Work 1-3 of 3

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Article

Sleep Disturbance Among HIV-Infected and Uninfected Veterans

by Julie A. Womack; Terrence E. Murphy; Harini Bathulapalli; Kathleen M. Akgun; Cynthia Gibert; Ken M. Kunisaki; David Rimland; Maria Rodriguez-Barradas; H. Klar Yaggi; Amy C. Justice; Nancy S. Redeker

2017

Subjects
  • Health Sciences, Nursing
  • Health Sciences, General
  • File Download

Article

Unhealthy Alcohol and Illicit Drug Use are Associated with Decreased Quality of HIV Care

by P. Todd Korthuis; David A. Fiellin; Kathleen A. McGinnis; Melissa Skanderson; Amy C. Justice; Adam J. Gordon; Donna Almario Doebler; Steven M. Asch; Lynn E. Fiellin; Kendall Bryant; Cynthia L. Gibert; Stephen Crystal; Matthew Bidwell Goetz; David Rimland; Maria C. Rodriguez-Barradas; Kevin L. Kraemer

2012

Subjects
  • Health Sciences, Immunology
  • Health Sciences, Epidemiology
  • Health Sciences, General
  • File Download
  • View Abstract

Abstract:Close

HIV-infected patients with substance use experience suboptimal health outcomes, possibly because of variations in care. OBJECTIVES: To assess the association between substance use and the quality of HIV care (QOC) received. RESEARCH DESIGN: Retrospective cohort study. SUBJECTS: HIV-infected patients enrolled in the Veterans Aging Cohort Study. MEASURES: We collected self-report substance use data and abstracted 9 HIV quality indicators (QIs) from medical records. Independent variables were unhealthy alcohol use (AUDIT-C score ≥4) and illicit drug use (self-report of stimulants, opioids, or injection drug use in past year). Main outcome was the percentage of QIs received, if eligible. We estimated associations between substance use and QOC using multivariable linear regression. RESULTS: The majority of the 3410 patients were male (97.4%) and black (67.0%) with a mean age of 49.1 years (SD = 8.8). Overall, 25.8% reported unhealthy alcohol use, 22% illicit drug use, and participants received 81.5% (SD = 18.9) of QIs. The mean percentage of QIs received was lower for those with unhealthy alcohol use versus not (59.3% vs. 70.0%, P < 0.001) and those using illicit drugs vs. not (57.8% vs. 70.7%, P < 0.001). In multivariable models, unhealthy alcohol use (adjusted β-2.74; 95% confidence interval:-4.23 to-1.25) and illicit drug use (adjusted β-3.51; 95% CI:-4.99 to-2.02) remained inversely associated with the percentage of QIs received. CONCLUSIONS: Although the overall QOC for these HIV-infected Veteran patients was high, gaps persist for those with unhealthy alcohol and illicit drug use. Interventions that address substance use in HIV-infected patients may improve the QOC received.

Article

Medical Intensive Care Unit Admission Among Patients With and Without HIV, Hepatitis C Virus, and Alcohol-Related Diagnoses in the United States: A National, Retrospective Cohort Study, 1997-2014

by Christopher T. Rentsch; Janet P. Tate; Tessa Steel; Adeel A. Butt; Cynthia L. Gibert; Laurence Huang; Margaret Pisani; Guy W. Soo Hoo; Stephen Crystal; Maria C. Rodriguez-Barradas; Sheldon T. Brown; Matthew S. Freiberg; Christopher J. Graber; Joon W. Kim; David Rimland; Amy C. Justice; David A. Fiellin; Kristina A. Crothers; Kathleen M. Akgun

2019

Subjects
  • Health Sciences, Medicine and Surgery
  • Health Sciences, Public Health
  • File Download
  • View Abstract

Abstract:Close

Background:HIV, hepatitis C virus (HCV), and alcohol-related diagnoses (ARD) independently contribute increased risk of all-cause hospitalization. We sought to determine annual medical intensive care unit (MICU) admission rates and relative risk of MICU admission between 1997 and 2014 among people with and without HIV, HCV, and ARD, using data from the largest HIV and HCV care provider in the United States. Setting:Veterans Health Administration. Methods:Annual MICU admission rates were calculated among 155,550 patients in the Veterans Aging Cohort Study by HIV, HCV, and ARD status. Adjusted rate ratios and 95% confidence intervals (CIs) were estimated with Poisson regression. Significance of trends in age-adjusted admission rates were tested with generalized linear regression. Models were stratified by calendar period to identify shifts in MICU admission risk over time.Results:Compared to HIV-/HCV-/ARD- patients, relative risk of MICU admission decreased among HIV-mono-infected patients from 61% (95% CI: 1.56 to 1.65) in 1997-2009% to 21% (95% CI: 1.16 to 1.27) in 2010-2014, increased among HCV-mono-infected patients from 22% (95% CI: 1.16 to 1.29) in 1997-2009% to 54% (95% CI: 1.43 to 1.67) in 2010-2014, and remained consistent among patients with ARD only at 46% (95% CI: 1.42 to 1.50). MICU admission rates decreased by 48% among HCV-uninfected patients (P-trend <0.0001) but did not change among HCV+ patients (P-trend = 0.34). Conclusion:HCV infection and ARD remain key contributors to MICU admission risk. The impact of each of these conditions could be mitigated with combination of treatment of HIV, HCV, and interventions targeting unhealthy alcohol use.
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