Skip to navigation Skip to content
  • Woodruff
  • Business
  • Health Sciences
  • Law
  • MARBL
  • Oxford College
  • Theology
  • Schools
    • Undergraduate

      • Emory College
      • Oxford College
      • Business School
      • School of Nursing

      Community

      • Emory College
      • Oxford College
      • Business School
      • School of Nursing
    • Graduate

      • Business School
      • Graduate School
      • School of Law
      • School of Medicine
      • School of Nursing
      • School of Public Health
      • School of Theology
  • Libraries
    • Libraries

      • Robert W. Woodruff
      • Business
      • Chemistry
      • Health Sciences
      • Law
      • MARBL
      • Music & Media
      • Oxford College
      • Theology
    • Library Tools

      • Course Reserves
      • Databases
      • Digital Scholarship (ECDS)
      • discoverE
      • eJournals
      • Electronic Dissertations
      • EmoryFindingAids
      • EUCLID
      • ILLiad
      • OpenEmory
      • Research Guides
  • Resources
    • Resources

      • Administrative Offices
      • Emory Healthcare
      • Academic Calendars
      • Bookstore
      • Campus Maps
      • Shuttles and Parking
      • Athletics: Emory Eagles
      • Arts at Emory
      • Michael C. Carlos Museum
      • Emory News Center
      • Emory Report
    • Resources

      • Emergency Contacts
      • Information Technology (IT)
      • Outlook Web Access
      • Office 365
      • Blackboard
      • OPUS
      • PeopleSoft Financials: Compass
      • Careers
      • Human Resources
      • Emory Alumni Association
  • Browse
    • Works by Author
    • Works by Journal
    • Works by Subject
    • Works by Dept
    • Faculty by Dept
  • For Authors
    • How to Submit
    • Deposit Advice
    • Author Rights
    • Publishing Your Data
    • FAQ
    • Emory Open Access Policy
    • Open Access Fund
  • About OpenEmory
    • About OpenEmory
    • About Us
    • Citing Articles
    • Contact Us
    • Privacy Policy
    • Terms of Use
 
Contact Us

Filter Results:

Year

  • 2017 (7)
  • 2018 (7)
  • 2020 (7)
  • 2013 (5)
  • 2014 (5)
  • 2012 (4)
  • 2015 (4)
  • 2016 (4)
  • 2019 (4)
  • 2021 (4)
  • 2022 (4)
  • 2009 (2)
  • 2006 (1)
  • 2011 (1)

Author

  • Yoganathan, Ajit (7)
  • Liu, Tian (5)
  • Yang, Xiaofeng (5)
  • Lei, Yang (4)
  • Wang, Tonghe (4)
  • Curran Jr, Walter (3)
  • Fogel, Mark (3)
  • Fogel, Mark A. (3)
  • Haggerty, Christopher M. (3)
  • Khiabani, Reza H. (3)
  • Tang, Elaine (3)
  • Beitler, Jonathan J (2)
  • Bellot, Gaetan (2)
  • Bron, Patrick (2)
  • Chen, Marcus Y. (2)
  • Ferlito, Alfio (2)
  • Fu, Yabo (2)
  • Hutton, William (2)
  • Ke, Yonggang (2)
  • Kong, Jun (2)
  • Li, Longchuan (2)
  • Mahle, William (2)
  • Mirabella, Lucia (2)
  • Newburger, Jane W. (2)
  • Ohye, Richard G. (2)
  • Restrepo, Maria (2)
  • Rhee, John (2)
  • Rinaldo, Alessandra (2)
  • Tannenbaum, Allen (2)
  • Teodoro, George (2)
  • Xerogeanes, John (2)
  • Abbara, Suhny (1)
  • Abrahamse, Paul (1)
  • Adams, Lucas J. (1)
  • Ahearn, Briggs (1)
  • Al-Hakim, Ramsey (1)
  • Alonas, Eric (1)
  • Amedi, A (1)
  • Anwar, Abbas (1)
  • Armstrong, G T (1)
  • Armstrong, GT (1)
  • Atz, Andrew M. (1)
  • Auffermann, William F (1)
  • Babb, James (1)
  • Baffa, Jeanne Marie (1)
  • Balasubramaniam, Muthukumar (1)
  • Ballard, DH (1)
  • Bar-Cohen, Yaniv (1)
  • Barrett, Lisa Feldman (1)
  • Barros-Rios, Jaime (1)
  • Bates, James (1)
  • Becerra-Culqui, Tracy (1)
  • Bhatti, PT (1)
  • Black, James C. (1)
  • Borich, Michael (1)
  • Boruta, Richard J. (1)
  • Boyd, Lara A. (1)
  • Bradlyn, Andrew (1)
  • Bradshaw Ghavidel, Beth (1)
  • Branch, T.P. (1)
  • Brothers, Matthew (1)
  • Bruno, Mary (1)
  • Burns, Kristin M. (1)
  • Cain, Nicole (1)
  • Chaffins, Brandon D. (1)
  • Chen, Richard (1)
  • Chen, Shan (1)
  • Chen, Shan (1)
  • Choo, Hyojung (1)
  • Chow, EJ (1)
  • Chowdhury, Shahryar (1)
  • Chung, CK (1)
  • Cnota, James (1)
  • Cnota, James F. (1)
  • Colan, Steven D. (1)
  • Cole, M (1)
  • Colucci, Jennifer K. (1)
  • Constine, LS (1)
  • Conticello, Vincent (1)
  • Coopmans, Fraukje M. T. (1)
  • Corporan, D (1)
  • Corry, June (1)
  • Court, LE (1)
  • Crocker, Ian (1)
  • Curran, Walter (1)
  • Curran, Walter J (1)
  • Czosek, Richard J. (1)
  • Dagincourt, Nicholas (1)
  • Danthi, Pranav (1)
  • Dasi, Lakshmi P. (1)
  • Dasi, Lakshmi P. (1)
  • De Zelicourt, Diane (1)
  • Decker, Jamie A. (1)
  • Descoteaux, M (1)
  • Ding, Yichen (1)
  • Dixon, Richard A. (1)
  • Dong, Xue (1)
  • Dragulescu, Andreea (1)
  • Dunbar-Masterson, Carolyn (1)
  • Duncan, James (1)

Subject

  • Engineering, Biomedical (20)
  • Health Sciences, Medicine and Surgery (17)
  • Health Sciences, Radiology (16)
  • Health Sciences, Oncology (7)
  • Health Sciences, General (5)
  • Biology, Neuroscience (3)
  • Biology, Radiation (3)
  • Chemistry, Biochemistry (3)
  • Health Sciences, Public Health (3)
  • Chemistry, General (2)
  • Computer Science (2)
  • Health Sciences, Epidemiology (2)
  • Health Sciences, Health Care Management (2)
  • Health Sciences, Rehabilitation and Therapy (2)
  • Biology, Bioinformatics (1)
  • Biology, Cell (1)
  • Biology, General (1)
  • Biology, Genetics (1)
  • Biology, Molecular (1)
  • Biology, Virology (1)
  • Biophysics, General (1)
  • Biophysics, Medical (1)
  • Engineering, Chemical (1)
  • Engineering, Robotics (1)
  • Health Sciences, Human Development (1)
  • Health Sciences, Immunology (1)
  • Health Sciences, Pharmacology (1)
  • Physics, General (1)
  • Psychology, Cognitive (1)
  • Psychology, Physiological (1)

Journal

  • Journal of Thoracic and Cardiovascular Surgery (3)
  • Proceedings of the National Academy of Sciences (3)
  • Circulation: Cardiovascular Imaging (2)
  • Physics in Medicine and Biology (2)
  • 2015 IEEE 12TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI) (1)
  • ACADEMIC RADIOLOGY (1)
  • ADVANCED SCIENCE (1)
  • ADVANCES IN THERAPY (1)
  • American Heart Journal (1)
  • Annals of Thoracic Surgery (1)
  • BMC Medical Informatics and Decision Making (1)
  • Biomedical Optics Express (1)
  • Biotechnology for Biofuels (1)
  • Cancer Treatment Reviews (1)
  • Circulation (1)
  • Concurrency and Computation: Practice and Experience (1)
  • ELIFE (1)
  • FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (1)
  • FRONTIERS IN CARDIOVASCULAR MEDICINE (1)
  • Frontiers in Oncology (1)
  • HUMAN BRAIN MAPPING (1)
  • Head and Neck (1)
  • Human Brain Mapping (1)
  • International Journal for Numerical Methods in Biomedical Engineering (1)
  • International Journal of Cardiovascular Imaging (1)
  • Investigative Radiology (1)
  • JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS (1)
  • JOURNAL OF ORTHOPAEDIC TRAUMA (1)
  • Journal of Applied Clinical Medical Physics (1)
  • Journal of Biomechanical Engineering (1)
  • Journal of Biomechanics (1)
  • Journal of Bone and Joint Surgery, American Volume (1)
  • Journal of Cancer Survivorship (1)
  • Journal of Cardiovascular Computed Tomography (1)
  • Journal of Cardiovascular Magnetic Resonance (1)
  • Journal of Orthopaedic Surgery and Research (1)
  • Journal of Pediatric Orthopaedics (1)
  • Journal of Virology (1)
  • Knee Surgery, Sports Traumatology, Arthroscopy (1)
  • Magnetic Resonance in Medicine (1)
  • Medical Image Analysis (1)
  • NEUROSPINE (1)
  • Nature (1)
  • OTO Open (1)
  • Orthopaedic Journal of Sports Medicine (1)
  • PHYSICS IN MEDICINE AND BIOLOGY (1)
  • PLoS Computational Biology (1)
  • PLoS ONE (1)
  • RADIOTHERAPY AND ONCOLOGY (1)
  • Restorative Neurology and Neuroscience (1)
  • Reviews in Endocrine and Metabolic Disorders (1)
  • Technology in Cancer Research and Treatment (1)
  • mBio (1)

Keyword

  • technolog (58)
  • biomedicin (51)
  • life (51)
  • imag (25)
  • medic (21)
  • medicin (20)
  • nuclear (19)
  • radiolog (19)
  • cardiac (15)
  • system (15)
  • comput (14)
  • surgeri (13)
  • cardiolog (12)
  • cardiovascular (12)
  • engin (11)
  • model (10)
  • biomed (9)
  • heart (9)
  • ct (8)
  • mri (8)
  • other (8)
  • radiat (8)
  • tomographi (8)
  • topic (8)
  • total (8)
  • cancer (7)
  • connect (7)
  • multidisciplinari (7)
  • oncolog (7)
  • analysi (6)
  • dose (6)
  • magnet (6)
  • network (6)
  • orthoped (6)
  • patient (6)
  • reson (6)
  • segment (6)
  • therapi (6)
  • accuraci (5)
  • angiographi (5)
  • biolog (5)
  • brain (5)
  • cavopulmonari (5)
  • cell (5)
  • children (5)
  • dynam (5)
  • free (5)
  • function (5)
  • head (5)
  • in (5)
  • motion (5)
  • procedur (5)
  • qualiti (5)
  • singl (5)
  • structur (5)
  • 3 (4)
  • acl (4)
  • anterior (4)
  • computedtomographi (4)
  • cruciat (4)
  • deform (4)
  • diseas (4)
  • flap (4)
  • fluid (4)
  • human (4)
  • knee (4)
  • learn (4)
  • ligament (4)
  • loss (4)
  • manag (4)
  • microscopi (4)
  • molecular (4)
  • mr (4)
  • neck (4)
  • neurolog (4)
  • neurosci (4)
  • norwood (4)
  • oper (4)
  • outcom (4)
  • pediatr (4)
  • protein (4)
  • radiotherapi (4)
  • respiratori (4)
  • risk (4)
  • simul (4)
  • sport (4)
  • surgic (4)
  • treatment (4)
  • trial (4)
  • vascular (4)
  • ventricl (4)
  • biochemistri (3)
  • blood (3)
  • bone (3)
  • breast (3)
  • compress (3)
  • conduit (3)
  • correct (3)

Author affiliation

  • Adjunct Faculty, School of Electrical and Computer Engineering, Georgia Institute of Technology (1)

Author department

  • BME: Admin (15)
  • Rad Onc: Admin (8)
  • Orthopaedics: Admin (7)
  • Peds: Children's Hrt Ctr (4)
  • Epidemiology (3)
  • Rad: MR Research Lab (3)
  • Surgery: Thoracic (3)
  • Anesthesiology: Admin (2)
  • BMI: Admin (2)
  • Biochem: Admin (2)
  • Peds: Marcus Center (2)
  • Rad: Admin (2)
  • Rad: Cardio Thoracic (2)
  • Anthropology (1)
  • Biology (1)
  • Biostatistics (1)
  • Cell Biology: Admin (1)
  • Chemistry (1)
  • Emory Vaccine Center (1)
  • HMO: Med Onc (1)
  • Hum Gen: Admin (1)
  • Medicine: Cardiology (1)
  • Medicine: Endocrinology (1)
  • Medicine: Pulmonary (1)
  • NND-Neuroscience (1)
  • Ofc Research Fund Supprt (1)
  • Ophthal: Admin (1)
  • Otolaryngology:Admin (1)
  • Peds: Emory LOBP (1)
  • Peds: Infectious Disease (1)
  • Peds: Survivor (1)
  • Physics (1)
  • Rad: Med Phys & Quad Img (1)
  • Rad: Neuroradiology (1)
  • Rad: Nuclear Medicine (1)
  • Rad: Physics & Comp Lab (1)
  • Rad: Rsch Labs - Gen Adm (1)
  • Rehab: DPT Program (1)
  • Surgery: Grady Surgery (1)
  • Surgery: Oncology (1)
  • Survivor (1)
  • Urology: Admin (1)

Search Results for all work with filters:

  • scienc
  • reconstruct

Work 1-10 of 59

Sorted by relevance
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
>

Article

Assessment of knee laxity using a robotic testing device: a comparison to the manual clinical knee examination

by T.P. Branch; S.K. Stinton; R. Siebold; H.I. Freedberg; C.A. Jacobs; William Hutton

2017

Subjects
  • Engineering, Robotics
  • Engineering, Biomedical
  • File Download
  • View Abstract

Abstract:Close

Purpose: The purpose of this study was to collect knee laxity data using a robotic testing device. The data collected were then compared to the results obtained from manual clinical examination. Methods: Two human cadavers were studied. A medial collateral ligament (MCL) tear was simulated in the left knee of cadaver 1, and a posterolateral corner (PLC) injury was simulated in the right knee of cadaver 2. Contralateral knees were left intact. Five blinded examiners carried out manual clinical examination on the knees. Laxity grades and a diagnosis were recorded. Using a robotic knee device which can measure knee laxity in three planes of motion: anterior–posterior, internal–external tibia rotation, and varus–valgus, quantitative data were obtained to document tibial motion relative to the femur. Results: One of the five examiners correctly diagnosed the MCL injury. Robotic testing showed a 1.7° larger valgus angle, 3° greater tibial internal rotation, and lower endpoint stiffness (11.1 vs. 24.6 Nm/°) in the MCL-injured knee during varus–valgus testing when compared to the intact knee and 4.9 mm greater medial tibial translation during rotational testing. Two of the five examiners correctly diagnosed the PLC injury, while the other examiners diagnosed an MCL tear. The PLC-injured knee demonstrated 4.1 mm more lateral tibial translation and 2.2 mm more posterior tibial translation during varus–valgus testing when compared to the intact knee. Conclusions: The robotic testing device was able to provide objective numerical data that reflected differences between the injured knees and the uninjured knees in both cadavers. The examiners that performed the manual clinical examination on the cadaver knees proved to be poor at diagnosing the injuries. Robotic testing could act as an adjunct to the manual clinical examination by supplying numbers that could improve diagnosis of knee injury. Level of evidence: Level II.

Article

Cooperative and out-of-core execution of the irregular wavefront propagation pattern on hybrid machines with Intel((R)) Xeon Phi

by Jeremias Gomes; Alba C. M. A. de Melo; Jun Kong; Tahsin Kurc; Joel H. Saltz; George Teodoro

2018

Subjects
  • Computer Science
  • Biology, Bioinformatics
  • File Download
  • View Abstract

Abstract:Close

The Irregular Wavefront Propagation Pattern (IWPP) is a core computing structure in several image analysis operations. Efficient implementation of IWPP on the Intel Xeon Phi is difficult because of the irregular data access and computation characteristics. The traditional IWPP algorithm relies on atomic instructions, which are not available in the SIMD set of the Intel Phi. To overcome this limitation, we have proposed a new IWPP algorithm that can take advantage of non-atomic SIMD instructions supported on the Intel Xeon Phi. We have also developed and evaluated methods to use CPU and Intel Phi cooperatively for parallel execution of the IWPP algorithms. Our new cooperative IWPP version is also able to handle large out-of-core images that would not fit into the memory of the accelerator. The new IWPP algorithm is used to implement the Morphological Reconstruction and Fill Holes operations, which are operations commonly found in image analysis applications. The vectorization implemented with the new IWPP has attained improvements of up to about 5× on top of the original IWPP and significant gains as compared to state-of-the-art the CPU and GPU versions. The new version running on an Intel Phi is 6.21× and 3.14× faster than running on a 16-core CPU and on a GPU, respectively. Finally, the cooperative execution using two Intel Phi devices and a multi-core CPU has reached performance gains of 2.14× as compared to the execution using a single Intel Xeon Phi.

Article

PCLR: Phase-Constrained Low-Rank Model for Compressive Diffusion-Weighted MRI

by Hao Gao; Longchuan Li; Kai Zhang; Weifeng Zhou; Xiaoping Hu

2014

Subjects
  • Health Sciences, Radiology
  • Computer Science
  • File Download
  • View Abstract

Abstract:Close

Purpose: This work develops a compressive sensing approach for diffusion-weighted (DW) MRI.Theory and Methods: A phase-constrained low-rank (PCLR) approach was developed using the image coherence across the DW directions for efficient compressive DW MRI, while accounting for drastic phase changes across the DW directions, possibly as a result of eddy current, and rigid and nonrigid motions. In PCLR, a low-resolution phase estimation was used for removing phase inconsistency between DW directions. In our implementation, GRAPPA (generalized autocalibrating partial parallel acquisition) was incorporated for better phase estimation while allowing higher undersampling factor. An efficient and easy-to-implement image reconstruction algorithm, consisting mainly of partial Fourier update and singular value decomposition, was developed for solving PCLR.Results: The error measures based on diffusion-tensorderived metrics and tractography indicated that PCLR, with its joint reconstruction of all DW images using the image coherence, outperformed the frame-independent reconstruction through zero-padding FFT. Furthermore, using GRAPPA for phase estimation, PCLR readily achieved a four-fold undersampling.Conclusion: The PCLR is developed and demonstrated for compressive DW MRI. A four-fold reduction in k-space sampling could be readily achieved without substantial degradation of reconstructed images and diffusion tensor measures, making it possible to significantly reduce the data acquisition in DW MRI and/or improve spatial and angular resolutions.

Article

Impact of Initial Shunt Type on Echocardiographic Indices in Children After Single Right Ventricle Palliations The SVR Trial at 6 Years

by Peter C. Frommelt; Chenwei Hu; Felicia Trachtenberg; Jeanne Marie Baffa; Richard J. Boruta; Shahryar Chowdhury; James F. Cnota; Andreea Dragulescu; Jami C. Levine; Jimmy Lu; Laura Mercer-Rosa; Thomas A. Miller; Amee Shah; Timothy Slesnick; Gary Stapleton; Jessica Stelter; Pierre Wong; Jane W. Newburger

2019

Subjects
  • Health Sciences, Health Care Management
  • Health Sciences, Human Development
  • Health Sciences, Medicine and Surgery
  • File Download
  • View Abstract

Abstract:Close

Background: Heart size and function in children with single right ventricle (RV) anomalies may be influenced by shunt type at the Norwood procedure. We sought to identify shunt-related differences during early childhood after staged surgical palliations using echocardiography. Methods: We compared echocardiographic indices of RV, neoaortic, and tricuspid valve size and function at 14 months, pre-Fontan, and 6 years in 241 subjects randomized to a Norwood procedure using either the modified Blalock-Taussig shunt or RV-to-pulmonary-artery shunt. Results: At 6 years, the shunt groups did not differ significantly in any measure except for increased indexed neoaortic area in the modified Blalock-Taussig shunt. RV ejection fraction improved between pre-Fontan and 6 years in the RV-to-pulmonary artery shunt group but was stable in the modified Blalock-Taussig shunt group. For the entire cohort, RV diastolic and systolic size and functional indices were improved at 6 years compared with earlier measurements, and indexed tricuspid and neoaortic annular area decreased from 14 months to 6 years. The prevalence of ≥moderate tricuspid and neoaortic regurgitation was uncommon and did not vary by group or time period. Diminished RV ejection fraction at the 14-month study was predictive of late death/transplant; the hazard of late death/transplant when RV ejection fraction was <40% was tripled (hazard ratio, 3.18; 95% CI, 1.41-7.17). Conclusions: By 6 years after staged palliation, shunt type has not impacted RV size and function, and RV and valvar size and function show beneficial remodeling. Poor RV systolic function at 14 months predicts worse late survival independent of the initial shunt type.

Article

Viability of full-thickness skin grafts used for correction of cicatricial ectropion of lower eyelid in previously irradiated field in the periocular region

by Hee Joon Kim; Brent Hayek; Qasiem Nasser; Bita Esmaeli

2013

Subjects
  • Health Sciences, Medicine and Surgery
  • File Download
  • View Abstract

Abstract:Close

Background The purpose of this study was to evaluate the viability of skin grafts used for correction of cicatricial ectropion resulting from previous ablative surgery and radiotherapy for head and neck cancer and to report overall outcomes of cicatricial ectropion repair. Methods This is a retrospective, noncomparative case series of all consecutive patients with head and neck cancer who had been exposed to high-dose radiation therapy in their periocular region and had surgical correction of their lower eyelid cicatricial ectropion through placement of a full-thickness skin graft and a lower eyelid tightening procedure by the same surgeon. The primary outcome measure was skin graft viability. Secondary outcome measures comprised postoperative complications, the overall outcome of ectropion repair as judged by improvement in symptoms of exposure keratopathy, and dependence on lubricating eye drops and ointments, as well as cosmetic improvement measured through a grading scale based on the degree of inferior scleral show and/or tarsal conjunctival eversion. Results Twenty-five patients were eligible for the study. Nineteen men and 6 women had a median age of 63 years (range, 20-84 years). All 25 patients had high-dose radiation therapy for their head and neck cancer. All but 1 patient had major cancer ablative surgery performed before radiation therapy. Thirteen of 25 patients also received chemotherapy. There was 100% viability of the skin grafts used for the repair of lower eyelid cicatricial ectropion. There were a few postoperative complications including the need for revision surgery to correct residual ectropion in the lower eyelid in 2 patients, and a third patient required a revision surgery due to upper eyelid retraction and lagophthalmos after harvest of skin graft from the upper eyelid. Improvement was noted in the subjective symptoms in 22 of 25 patients (88%), whereas 17 patients (68%) were noted to have improvement in their clinical findings on slit lamp examination. All 20 patients, for whom good quality photos were available, had improvement in the degree of cicatricial lower eyelid ectropion as measured by the amount of inferior scleral show and tarsal conjunctival eversion, although 11 patients had some residual ectropion. All 20 had either good or excellent results in the appearance of their skin grafts. Conclusion Our findings suggest that full-thickness skin grafts are a nice option for correction of cicatricial lower eyelid ectropion in a previously radiated field; 100% of the grafts survived. The majority of patients had improvement of ocular surface damage and symptoms, with a decreased dependence on topical lubricants. All evaluable patients had improvement in the degree of cicatricial lower eyelid ectropion, although close to one-half of patients had some mild residual ectropion. The majority of patients had excellent appearance of the skin graft.

Article

Effect of Preoperative Gabapentin With a Concomitant Adductor Canal Block on Pain and Opioid Usage After Anterior Cruciate Ligament Reconstruction

by Briggs Ahearn; Arun Kumar; Ajay Premkumar; Heather A Samady; Michael Gottschalk; John W Xerogeanes; Spero Karas

2019

Subjects
  • Health Sciences, Rehabilitation and Therapy
  • Health Sciences, Medicine and Surgery
  • File Download
  • View Abstract

Abstract:Close

Background: An adductor canal block (ACB) and preoperative oral gabapentin have each been shown to decrease postoperative pain scores and opioid usage in patients undergoing anterior cruciate ligament (ACL) reconstruction. Purpose/Hypothesis: This study evaluated the efficacy of preoperative gabapentin on postoperative analgesia in patients who received an ACB. We hypothesized that patients undergoing ACL reconstruction with an ACB who utilized a single dose of preoperative oral gabapentin would have decreased pain and opioid consumption in the 24 to 72 hours after surgery compared with patients who did not utilize gabapentin. Study Design: Cohort study; Level of evidence, 3. Methods: Between January and October 2016, patients at a single institution who underwent ACL reconstruction and received an ACB were identified. Patients who underwent surgery before May 2016 were placed in the control group, and patients seen after May 2016 received a preoperative dose of gabapentin and were placed in the gabapentin group. All patients completed a pain log via a smartphone application to record pain scores and opioid usage after surgery. Results: A total of 74 patients were identified: 41 in the gabapentin group and 33 in the control group. There were no significant differences between groups in demographics and operative characteristics. There were no differences in pain scores on postoperative day 1 (gabapentin vs control: 5.53 vs 5.56; P =.95), day 2 (4.58 vs 4.83; P =.59), or day 3 (4.15 vs 3.87; P =.59). The mean opioid consumption in oral morphine equivalents was not different on postoperative day 1 (gabapentin vs control: 47.2 vs 48.1; P =.90), day 2 (29.9 vs 33.5; P =.60), or day 3 (17.4 vs 18.7; P =.80). Conclusion: Preoperative gabapentin did not reduce pain scores or opioid usage in patients who received an ACB and underwent ACL reconstruction in this retrospective cohort study.

Article

Liver Whole Slide Image Analysis for 3D Vessel Reconstruction

by Yanhui Liang; Fusheng Wang; Darren Treanor; Derek Magee; George Teodoro; Yangyang Zhu; Jun Kong

2015

Subjects
  • Engineering, Biomedical
  • Health Sciences, Radiology
  • File Download
  • View Abstract

Abstract:Close

The emergence of digital pathology has enabled numerous quantitative analyses of histopathology structures. However, most pathology image analyses are limited to two-dimensional datasets, resulting in substantial information loss and incomplete interpretation. To address this, we have developed a complete framework for three-dimensional whole slide image analysis and demonstrated its efficacy on 3D vessel structure analysis with liver tissue sections. The proposed workflow includes components on image registration, vessel segmentation, vessel cross-section association, object interpolation, and volumetric rendering. For 3D vessel reconstruction, a cost function is formulated based on shape descriptors, spatial similarity and trajectory smoothness by taking into account four vessel association scenarios. An efficient entropy-based Relaxed Integer Programming (eRIP) method is proposed to identify the optimal inter-frame vessel associations. The reconstructed 3D vessels are both quantitatively and qualitatively validated. Evaluation results demonstrate high efficiency and accuracy of the proposed method, suggesting its promise to support further 3D vessel analysis with whole slide images.

Article

Agreement between medical records and self-reports: Implications for transgender health research

by Joseph Gerth; Tracy Becerra-Culqui; Andrew Bradlyn; Darios Getahun; Enid M. Hunkeler; Timothy Lash; Andrea Millman; Rebecca Nash; Virginia P. Quinn; Brandi Robinson; Douglas Roblin; Michael J. Silverberg; Vin Tangpricha; Suma Vupputuri; Michael Goodman

2018

Subjects
  • Health Sciences, Medicine and Surgery
  • File Download
  • View Abstract

Abstract:Close

A key priority of transgender health research is the evaluation of long-term effects of gender affirmation treatment. Thus, accurate assessment of treatment receipt is critical. The data for this analysis came from an electronic medical records (EMR) based cohort of transgender individuals. A subset of cohort members were also asked to complete a self-administered survey. Information from the EMR was compared with survey responses to assess the extent of agreement regarding transmasculine (TM)/transfeminine (TF) status, hormone therapy receipt, and type of surgery performed. Logistic regression models were used to assess whether participant characteristics were associated with disagreement between data sources. Agreement between EMR and survey-derived information was high regarding TM/TF status (99%) and hormone therapy receipt (97%). Lower agreement was observed for chest reconstruction surgery (72%) and genital reconstruction surgery (84%). Using survey responses as the “gold standard”, both chest and genital reconstruction surgeries had high specificity (95 and 93%, respectively), but the corresponding sensitivities were low (49 and 68%, respectively). A lower proportion of TM had concordant results for chest reconstruction surgery (64% versus 79% for TF) while genital reconstruction surgery concordance was lower among TF (79% versus 89% for TM). For both surgery types, agreement was highest among the youngest participants. Our findings offer assurance that EMR-based data appropriately classify cohort participants with respect to their TM/TF status or hormone therapy receipt. However, current EMR data may not capture the complete history of gender affirmation surgeries. This information is useful in future studies of outcomes related to gender affirming therapy.

Article

Development and psychometric properties of a brief measure of subjective decision quality for breast cancer treatment

by Ken Resnicow; Paul Abrahamse; Rachel S Tocco; Sarah Hawley; Jennifer Griggs; Nancy Janz; Angela Fagerlin; Adrienne Wilson; Kevin Ward; Sheryl Gabram-Mendola; Steven Katz

2014

Subjects
  • Health Sciences, Oncology
  • Health Sciences, Medicine and Surgery
  • File Download
  • View Abstract

Abstract:Close

Background Breast cancer patients face several preference-sensitive treatment decisions. Feelings such as regret or having had inadequate information about these decisions can significantly alter patient perceptions of recovery and recurrence. Numerous objective measures of decision quality (e.g., knowledge assessments, values concordance measures) have been developed; there are far fewer measures of subjective decision quality and little consensus regarding how the construct should be assessed. The current study explores the psychometric properties of a new subjective quality decision measure for breast cancer treatment that could be used for other preference sensitive decisions. Methods 320 women aged 20–79 diagnosed with AJCC stage 0 – III breast cancer were surveyed at two cancer specialty centers. Decision quality was assessed with single items representing six dimensions: regret, satisfaction, and fit as well as perceived adequacy of information, time, and involvement. Women rated decision quality for their overall treatment experience and surgery, chemotherapy, and radiation decisions separately. Principle components was used to explore factor structure. After scales were formed, internal consistency was computed using Cronbach’s alpha. The association of each of the four final scales with patient characteristics scores was examined by Pearson correlation. Results For overall breast cancer treatment as well as surgery, chemotherapy, and radiation decisions, the six items yielded a single factor solution. Factor loadings of the six decision items were all above .45 across the overall and treatment-specific scales, with the exception of “Right for You” for chemotherapy and radiation. Internal consistency was 0.77, 0.85, 0.82, and 0.78 for the overall, surgery, chemotherapy, and radiation decision quality scales, respectively. Conclusions Our measure of subjective appraisal of breast cancer treatment decisions includes 5 related elements; regret and satisfaction as well as perceived adequacy of information, time, and involvement. Future research is needed to establish norms for the measure as is further psychometric testing, particularly to examine how it is associated with outcomes such as quality of life, psychological coping and objective decision quality.

Article

Achieving lambda/10 Resolution CW STED Nanoscopy with a Ti:Sapphire Oscillator

by Yujia Liu; Yichen Ding; Eric Alonas; Wenli Zhao; Philip Santangelo; Dayong Jin; James A. Piper; Junlin Teng; Qiushi Ren; Peng Xi

2012

Subjects
  • Engineering, Biomedical
  • Health Sciences, General
  • File Download
  • View Abstract

Abstract:Close

In this report, a Ti:Sapphire oscillator was utilized to realize synchronization-free stimulated emission depletion (STED) microscopy. With pump power of 4.6 W and sample irradiance of 310 mW, we achieved super-resolution as high as 71 nm. With synchronization-free STED, we imaged 200 nm nanospheres as well as all three cytoskeletal elements (microtubules, intermediate filaments, and actin filaments), clearly demonstrating the resolving power of synchronization-free STED over conventional diffraction limited imaging. It also allowed us to discover that, Dylight 650, exhibits improved performance over ATTO647N, a fluorophore frequently used in STED. Furthermore, we applied synchronization-free STED to image fluorescently-labeled intracellular viral RNA granules, which otherwise cannot be differentiated by confocal microscopy. Thanks to the widely available Ti:Sapphire oscillators in multiphoton imaging system, this work suggests easier access to setup super-resolution microscope via the synchronization-free STED.
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
>
Site Statistics
  • 28,513
  • Total Works
  • 7,481,406
  • Downloads
  • 98,345
  • Downloads This Year
  • 6,807
  • Faculty Profiles

Copyright © 2016 Emory University - All Rights Reserved
540 Asbury Circle, Atlanta, GA 30322-2870
(404) 727-6861
Privacy Policy | Terms & Conditions

v2.2.8-dev

Contact Us Recent and Popular Items
Download now