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Author Notes:

E.J. Kovacs, University of Colorado Denver, 12700 East 19th Ave., RC2, Mailstop 8620, Aurora, CO 80045, United States. Tel.: +1 303 724 8243. Email: eliozabeth.kovacs@cuanschutz.edu

The authors would like to thank the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the Alcohol Research Programs at the University of Colorado Anschutz Medical Campus and Loyola University Chicago for financial support for the meeting. Support was also provided by the National Institutes of Health (NIH) under award numbers R13AA020768 (EJK/MAC), R21 AA026295 (EJK), R01 AT010005 (LAB), P50 AA024333 (LEN), U01AA026938 (LEN), R01 AA027456 (LEN), R01 AA025854 (MK), R01AA015566 (SE), R01AA025996 (SE), R01AA015566 (MR), U01AA013498 (MR), R00-AA026336 (DS), R21-AA021555 (JJC), R21 AA021225 (JJC), T32 GM08750 (MAC), T32 AA013527 (MAC), F31 AA028147 (JE), R01 HL062996 (JBT), and R01 ES031087 (JBT). The following authors were supported by grants from Veterans Affairs: I01 BX004335 (EJK), 1 I21 RX002232 (LAB), I01 BX005413 (TAW), IS1 BX004790 (DS), and 510 BX000853 (JBT). TAW is the recipient of a Research Career Scientist Award (IK6 BX003781) from the Department of Veterans Affairs. The authors would like to thank Dr. Vivian Gahtan, Chair of Loyola University Chicago’s Department of Surgery, for supporting the meeting. In addition, we acknowledge the help of Renita Alis and Kim Stubbs from Loyola University Chicago and Debra Sartain and Victoria Bress from University of Colorado Denver Anschutz Medical Campus for logistical support. Lastly, we are grateful to Dr. H. Joe Wang from NIAAA for attending the scientific sessions remotely. This content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Subjects:

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Substance Abuse
  • Pharmacology & Pharmacy
  • Toxicology
  • ethanol
  • inflammation
  • liver
  • lung
  • myopathy
  • pneumonia
  • skin
  • stem cell
  • brain
  • cardiovasculardisease
  • ADULT
  • LUNG

New insights into the mechanism of alcohol-mediated organ damage via its impact on immunity, metabolism, and repair pathways: A summary of the 2021 Alcohol and Immunology Research Interest Group (AIRIG) meeting

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Journal Title:

ALCOHOL

Volume:

Volume 103

Publisher:

, Pages 1-7

Type of Work:

Article | Post-print: After Peer Review

Abstract:

On November 19th, 2021, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The 2021 meeting focused on how alcohol misuse is linked to immune system derangements, leading to tissue and organ damage, and how this research can be translated into improving treatment of alcohol-related disease. This meeting was divided into three plenary sessions: the first session focused on how alcohol misuse affects different parts of the immune system, the second session presented research on mechanisms of organ damage from alcohol misuse, and the final session highlighted research on potential therapeutic targets for treating alcohol-mediated tissue damage. Diverse areas of alcohol research were covered during the meeting, from alcohol's effect on pulmonary systems and neuroinflammation to epigenetic changes, senescence markers, and microvesicle particles. These presentations yielded a thoughtful discussion on how the findings can lead to therapeutic treatments for people suffering from alcohol-related diseases.

Copyright information:

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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