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Dimple Notani, dnotani@ncbs.res.in
The study was conceptualized and designed by Z.I., B.S., and D.N. Most experiments were performed by Z.I. with help from U.F. and K.W. B.S. performed NGS data analysis. A.P. performed NGS library preparation and sequencing. A.K.S. and R.S. assisted in data analysis. D.N., Z.I., B.S., and S.H. wrote the manuscript with input from J.T. All authors read and edited the manuscript.
We thank D.N. laboratory members, Ranveer Jayani and Amanjot Singh, for the discussions. We acknowledge support of the Department of Atomic Energy, Government of India, under project no. 12-R&D-TFR-5.04-0800 and intramural funds from National Center for Biological Sciences–Tata Institute of Fundamental Research (NCBS-TIFR) (to D.N.). D.N. is an EMBO Global Investigator. We also acknowledge the funding support from Wellcome-IA (IA/1/14/2/501539) and Department of Science and Technology core grant (CRG/2019/005714) to D.N. U.F. is supported by the Council of Scientific and Industrial Research (CSIR, Government of India) senior research fellowship. K.W. and A.K.S. are supported by the TIFR-NCBS graduate program. K.W. is also supported by the CSIR-SPM (Government of India) fellowship. The genome sequence described/used in this research was derived from a HeLa cell line. Henrietta Lacks, and the HeLa cell line that was established from her tumor cells without her knowledge or consent in 1951, have made significant contributions to scientific progress and advances in human health. We thank Henrietta Lacks, now deceased, and her surviving family members for their contributions to biomedical research. This study was reviewed by the National Institutes of Health HeLa Genome Data Access Working Group.
The authors declare no competing interests.
© 2023 Islam et al.; Published by Cold Spring Harbor Laboratory Press