Synchronised transcranial magnetic stimulation for substance use-disordered Veterans: protocol for the pilot sham-controlled acceptability trial

• Authors: Jonathan Jampel, Clark University; McKenzie J Quinn, Providence VA Medical Center; Jamie L Catalano, Brown University; Chelsie B Benca-Bachman, Providence VA Medical Center; Leslie Brick, Emory University; Noah S Philip, Providence VA Medical Center; Robert M Swift, Providence VA Medical Center; John E McGeary, Providence VA Medical Center
• Journal Title: BMJ Open
• Volume: Volume 13, Number 1
• Publisher: BMJ Journals | 2023-01-30
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.1136/bmjopen-2022-066175
• Subjects: Psychology, General; Health Sciences, Mental Health
• Keywords: Telemedicine; mental health; Substance misuse; Clinical trials

Abstract

Substance use disorders (SUDs) take an enormous toll on US Veterans and civilians alike. Existing empirically supported interventions vary by substance and demonstrate only moderate efficacy. Non-invasive brain stimulation represents an innovative treatment for SUDs, yet aspects of traditional neurostimulation may hinder its implementation in SUD populations. Synchronised transcranial magnetic stimulation (sTMS) uses rotating rare earth magnets to deliver low-field stimulation synchronised to an individual’s alpha peak frequency that is safe for at-home administration. The current trial aims to assess the acceptability and feasibility of sTMS, as well as the safety of at-home sTMS administration for substance-disordered Veterans.