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Author Notes:

David O. Garcia, davidgarcua@arizona.edu

DG, EV, RC, YG, and CS designed the research. EV and DG conducted the research. EV, DG, and AM analyzed data. All authors were involved in writing the paper and had final approval of the submitted and published versions.

The authors would like to acknowledge all participants for partaking in this study. As well, we would like to thank the University of Arizona Collaboratory for Metabolic Disease Prevention and Treatment for the space to complete the semi-structured interviews.

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Subject:

Research Funding:

This work was supported by the National Institute on Minority Health and Health Disparities (award number K01MD014761 to DG), the Emory Cancer Prevention and Control Research Network (CPCRN) (U48 DP006413 to YG), the National Cancer Institute of the National Institutes of Health under the awards for the Partnership of Native American Cancer Prevention U54CA143924 (UACC), and University of Arizona Core Facilities Pilot Program (to DG).

Keywords:

  • NAFLD
  • genetic risk
  • PNPLA3
  • Mexican-origin
  • men's health

Communicating PNPLA3 genetic risk status for NAFLD among Mexican-origin men

Tools:

Journal Title:

Frontiers in Public Health

Volume:

Volume 10

Publisher:

Type of Work:

Article | Final Publisher PDF

Abstract:

The burden of non-alcoholic fatty liver disease (NAFLD) continues to disproportionately impact under-resourced communities in the U.S., particularly Mexican-origin populations. Genetic polymorphisms such as the rs738409 C/G variant in patatin-like phospholipase domain-containing 3 (PNPLA3) have been associated with higher prevalence of and progression along the NAFLD spectrum. This qualitative study conducted in the U.S. Southwest aimed to assess Mexican-origin men's experience receiving genetic testing for PNPLA3 risk carrier status.

Copyright information:

© 2023 Villavicencio, Maldonado, Crocker, Guan, Stallman and Garcia.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
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