Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells (vol 67, pg 311, 2018)

• Authors: Tamson Moore, Loyola University Chicago; Courtney Regan Wagner, Loyola University Chicago; Gina M. Scurti, Loyola University Chicago; Kelli A. Hutchens, Loyola University Chicago; Constantinea Godellas, Loyola University Chicago; Ann Lau Clark, Loyola University Chicago; Elizabeth Motunrayo Kolawole, Emory University; Lance M. Hellman, University of Notre Dame; Nishant K. Singh, University of Notre Dame; Fernando A. Huyke, University of Notre Dame; Siao-Yi Wang, Loyola University Chicago; Kelly M. Calabrese, Loyola University Chicago; Heather D. Embree, Lentigen Technol Inc; Rimas Orentas, Lentigen Technol Inc; Keisuke Shirai, Medical University of South Carolina; Emilia Dellacecca, Loyola University Chicago; Elizabeth Garrett-Mayer, Medical University of South Carolina; Mingli Li, Medical University of South Carolina; Jonathan M. Eby, Loyola University Chicago; Patrick J. Stiff, Loyola University Chicago; Brian Evavold, Emory University; Brian M. Baker, University of Notre Dame; I. Caroline Le Poole, Loyola University Chicago; Boro Dropulic, Lentigen Technol Inc; Joseph I. Clark, Loyola University Chicago; Michael I. Nishimura, Loyola University Chicago
• Journal Title: CANCER IMMUNOLOGY IMMUNOTHERAPY
• Volume: Volume 67, Number 2
• Publisher: SPRINGER | 2018-02-01, Pages 327-327
• Type of Work: Article | Post-print: After Peer Review
• Publisher DOI: http://doi.org/10.1007/s00262-017-2102-z
• Subjects: Health Sciences, Immunology; Health Sciences, Oncology
• Keywords: Science & Technology; Life Sciences & Biomedicine; Oncology; Immunology

Abstract

The authors would like to make the following corrections to the published article.Prior therapy for Patient 3 was high-dose IL-2, vemurafenib, ipilimumab, and dabrafenib (Table 1).TIL 1383I TCR complexes were tethered to the CM5 sensor surface and HLA-A2-tyrosinase complexes were injected over the surface (Methods and Fig. 5). The solution (3D) affinity of the TIL 1383I TCR was 13 μM (Fig. 5a and text).