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Jun Yin, junyin@gsu.edu; Yury O. Chernoff, yury.chernoff@biology.gatech.edu
B.Z., N.S., Y.O.C. and J.Y. conceived the overall idea and designed the experiments. Y.W., S.F., G.C., R.G., L.Z., D.D. and N.S. performed experiments. T.A.C., M.L., and H.K. provided technical guidance and/or intellectual input. Y.W., S.F., G.C., R.G., B.Z., N.S., Y.O.C. and J.Y. analyzed data, interpreted results, drafted and edited the manuscript. B.Z., N.S., Y.O.C. and J.Y. acquired funding. All authors reviewed and approved the final version of the manuscript.
We thank Lu Zhu and Scott D. Emr (Cornell University), David J. Katzmann (Mayo Clinic College of Medicine), Rosine Haguenauer-Tsapis (Institut Jacques Monod, France) and Pierre Morsomme (Louvain Institute of Biomolecular Science and Technology, Belgium) for kindly sharing materials and helpful discussions. We also thank Milo Fasken and Anita Corbett (Emory University) for technical advice.
The authors declare no competing interests.
This work was supported by grants from National Natural Science Foundation of China (31770921 and 31971187 to B.Z.), NIH (R01GM114308 to N. S. and R01GM104498 to J.Y.), and NSF (1817976 to Y. O. C. and 1710460 to J.Y.).