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An-Kwok Ian Wong, MD, PhD, Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University, Three Genome Court, PO Box 103050, Durham, NC 27710. Email: med@aiwong.com
Dr Wong had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Lough and Celi are co–senior authors. Concept and design: Wong, Charpignon, Kim, Carvalho, Holder, Buchman, Lough, Celi. Acquisition, analysis, or interpretation of data: Wong, Charpignon, Kim, Josef, de Hond, Fojas, Tabaie, Liu, Mireles-Cabodevila, Kamaleswaran, Madushani, Adhikari, Steyerberg, Lough, Celi. Drafting of the manuscript: Wong, Charpignon, Kim, Fojas, Mireles-Cabodevila, Lough, Celi. Critical revision of the manuscript for important intellectual content: Wong, Charpignon, Kim, Josef, de Hond, Tabaie, Liu, Mireles-Cabodevila, Carvalho, Kamaleswaran, Madushani, Adhikari, Holder, Steyerberg, Buchman, Lough, Celi. Statistical analysis: Wong, Charpignon, Kim, Josef, de Hond, Fojas, Tabaie, Madushani, Adhikari, Steyerberg, Celi. Administrative, technical, or material support: Wong, Liu. Supervision: Kamaleswaran, Adhikari, Holder, Buchman, Celi.
Dr Wong reported holding equity and management roles in Ataia Medical outside the submitted work. Dr Josef reported receiving grants from the National Institutes of Health during the conduct of the study. Dr Madushani reported receiving grants from the National Institute on Drug Abuse outside the submitted work. Dr Holder reported receiving grants from the National Institutes of Health during the conduct of the study and receiving speakers’ fees from Baxter international outside the submitted work. Dr Buchman reported that Emory University received funding from the US government for Dr Buchman’s role as senior advisor and IPA to the Division of Research, Innovation, and Ventures within BARDA; furthermore, he reported serving as editor in chief of Critical Care Medicine and receiving grants from Henry M. Jackson Foundation. No other disclosures were reported.
Dr Wong is supported by grant 2T32GM095442 from the National Institute of General Medical Sciences and the clinical and translational science award pilot informatics grant by the National Center for Advancing Translation Science under award UL1TR002378.
Dr Kamaleswaran is supported by grant 17267 from the Michael J. Fox Foundation.
Dr Josef is supported by grant 2T32GM095442 from the National Institute of General Medical Sciences.
Dr Tabaie was funded by the Surgical Critical Care Initiative (SC2i), the Department of Defense’s Defense Health Program Joint Program Committee 6/Combat Casualty Care (grants USUHS HT9404-13-1-0032 and HU0001-15-2-0001).
Dr Holder is supported by the National Institute for General Medical Sciences under award number K23GM137182 and the National Center for Advancing Translational Sciences of the National Institutes of Health under award number UL1TR002378.
Dr Buchman is supported by the Society of Critical Care Medicine and the Biomedical Advanced Research and Development Authority.
Dr Celi is funded by the National Institute of Health through grant NIBIB R01 EB017205.
2021 Wong AKI et al. JAMA Network Open.