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Ankur Singh, ankur.singh@gatech.edu
P.L.G. conducted all PEG-4MAL hydrogel studies, young and aged animal studies, bacterial antigen studies, and analyzed data with A.S. K.L performed comparisons between hydrogel chemistries and imaging. J.C. provided single-cell RNA sequencing on lymph node stromal cells and advice on germinal center biology. S.P and I.B. generated bacterial proteins, membranes, and western blots. A.S and P.G wrote the initial manuscript, revision, and all authors reviewed the manuscript and provided feedback. The concept was conceived by A.S. and funding was generated by A.S.
The authors acknowledge financial support from the National Institute of Allergy and Infectious Diseases of the US National Institutes of Health (5R01AI132738-03 awarded to A.S.), a US National Science Foundation CAREER award (DMR-1554275 awarded to A.S.), and the Innovative Molecular Analysis Technology program of the US National Cancer Institute (NIH R33-CA212968-01 awarded to A.S.). The authors acknowledge financial support from the Immunoengineering T32 training grant to S.P. (NIH and NIBIB, 1T32EB023860-01A1) and NIH 1S10RR025502 funding for the shared Zeiss LSM 710 Confocal Microscope, awarded to the Cornell University Biotechnology Resource Center. Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the funding agency.
The authors declare that they have no competing interests.