Editorial: Bioengineering and Biotechnology Approaches in Cardiovascular Sciences

• Authors: Jianyi Zhang, University of Alabama Birmingham; Martin L Tomov, Emory University; James JH Chong, University of Sydney; Philippe Menasché, University of Alabama Birmingham; Vahid Serpooshan, Emory University
• Journal Title: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
• Volume: Volume 9
• Publisher: FRONTIERS MEDIA SA | 2021-08-20, Pages 746435-746435
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.3389/fbioe.2021.746435
• Subjects: Engineering, Biomedical; Health Sciences, Medicine and Surgery
• Keywords: Science & Technology; Life Sciences & Biomedicine; Biotechnology & Applied Microbiology; Multidisciplinary Sciences; Science & Technology - Other Topics; bioengineering; biotechnologhy; cardiovascular medicine; tissue engieering; stem cell therapies

Abstract

Medical science has often looked to the fields of bioengineering and biotechnology as tools that can facilitate the clinical translation of new therapeutic strategies. This Research Topic, Bioengineering and Biotechnology Approaches in Cardiovascular Sciences, focuses on cardiovascular bioengineering principles that seek to develop cells and tissues that fully recapitulate the functional properties of their native analogs. Early studies were frequently limited by a lack of cells, especially cardiomyocytes (CMs), but progress has accelerated since the development of techniques for reprogramming somatic cells into induced pluripotent stem cells (iPSCs) and then differentiating them into nearly any desired lineage. Here, we present a collection of 13 original research and review articles that provide the reader with a broad overview of recent discoveries and innovations that may expedite the use of bioengineered cells and tissues for therapeutic applications, disease modeling, and drug testing.