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Dr. Changwon Park, 1501 Kings Hwy, Shreveport, LA 71103, USA. Tel: +13186758856, FAX: +1 (318)675-6005. Email: cpar13@lsuhsc.edu
Dr. Kyunghee Choi, Campus Box 8118, 660 S. Euclid Ave. St. Louis, MO, 63110-1093, USA. Tel: +1 3143628716, FAX: +1 314-747-0809. Email: kchoi@wustl.edu
We thank Mikala Egeblad at Cold Spring Harbor Laboratory for the generous gift of the MMTV-PyMT mice. We want to thank our colleagues at Washington University, Kory Lavine for MCEC cells, Andrew Yoo for BJ-5ta cells, Katherine Weilbaecher for PyMT-BO1-GFP-Luc cells, Luis Batista for pCDH-(LB12-FLAG-TERT)-EF1-NEO plasmid. We thank Robert D. Schreiber at Washington University for 1956 sarcoma cells and helpful suggestions with experimental design and data interpretation. We also want to thank Alexander S Krupnick at the University of Virginia for providing LLC-GFP cells. We thank Mike White and the Genome Engineering and iPSC Center (GEIC) at Washington University in St. Louis for the generation of Myct1 KO mice using CRISPR/CAS9 technology. We also thank Washington University Center for Cellular Imaging (WUCCI) and Pathology FACS core for providing access to the light microscopes and FACS facility, respectively. We thank Attila Kovacs and Carla J. Weinheimer of the Mouse Cardiovascular Phenotyping Core at Washington University School of Medicine for the echocardiogram analysis.
Samuel A. Wickline has Equity in Trasir Therapeutics, Inc. Ashraf Ul Kabir and Kyunghee Choi have a patent pending relating to this work (Application Number: 63/093,595; Title: COMPOSITIONS AND METHODS FOR MODULATING MYCT1). All other authors declare that they have no competing interests.
This work was supported by the NIH grants R01HL149954 (to K.C.), R01HL55337 (to K.C), R01HL119291 (to C.P), and K08HL135400 (to C.M.H), Children’s Heart Research and Outcomes Center and Children’s Healthcare of Atlanta 00060337 (to C.P.) and Mallinckrodt Challenge Grant (to K.C. and D.H.F.).