About this item:

56 Views | 26 Downloads

Author Notes:

David G. Lynn, dlynn2@emory.edu

We thank Hong Yi and Jeanette Taylor from the Robert P. Apkarian Electron Microscopy Core of Emory University for Electron Microscopy assistance, Dr Bing Wang and Dr Shaoxiong Wu from the Emory NMR Center for NMR assistance, and Dr Fred Strobel for mass spectrometry analysis. We acknowledge Pieter Burger for access to MacroModel and the processing power to run minimizations.

There are no conflicts to declare.

Subjects:

Research Funding:

The research was supported by grants from NSF CHE-1507932 and NSF/DMR-BSF 1610377, and NIH Alzheimer's Disease Research Center: P50AG025688.

Keywords:

  • Science & Technology
  • Physical Sciences
  • Chemistry, Multidisciplinary
  • Chemistry

Chemical control of peptide material phase transitions

Tools:

Journal Title:

CHEMICAL SCIENCE

Volume:

Volume 12, Number 8

Publisher:

, Pages 3025-3031

Type of Work:

Article | Final Publisher PDF

Abstract:

Progressive solute-rich polymer phase transitions provide pathways for achieving ordered supramolecular assemblies. Intrinsically disordered protein domains specifically regulate information in biological networksviaconformational ordering. Here we consider a molecular tagging strategy to control ordering transitions in polymeric materials and provide a proof-of-principle minimal peptide phase network captured with a dynamic chemical network.

Copyright information:

© The Royal Society of Chemistry

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License (https://creativecommons.org/licenses/by-nc-sa/3.0/rdf).
Export to EndNote