Scoring sleep using respiration and movement-based features

• Authors: H Kloefkorn, Emory University School of Medicine; LM Aiani, Emory University School of Medicine; Shawn Hochman, Emory University; Nigel Pedersen, Emory University
• Journal Title: MethodsX
• Volume: Volume 9
• Publisher: Elsevier B.V. | 2022-01-01, Pages 101682-101682
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.1016/j.mex.2022.101682
• Subjects: Health Sciences, Medicine and Surgery
• Keywords: Electric field sensor; Noninvasive; Rodent; Sleep scoring

Abstract

Rules derived from standard Rechtschaffen and Kales criteria were developed to accurately score rodent sleep into wake, rapid eye movement (REM) sleep, and non-REM sleep using movements detected by non-contact electric field (EF) sensors. • Using this method, rodent sleep can be scored using only respiratory and gross body movements as a validated, non-invasive alternative to electrode techniques. • The methodology and rules established for EF sensor-based sleep scoring were easily learned and implemented. • Examples of expert-scored files are included here to help novice scorers self-train to score sleep. Though validated in mice, sleep scoring using respiratory movements has the potential for application in other species and through other movement-based technologies beyond EF sensors.