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Daniel H. Leung, MD, FAASLD, Associate Professor of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Gastroenterology, Hepatology, and Nutrition, Director of Hepatology and Liver Transplant Medicine, Medical Director, Viral Hepatitis Program; 6621 Fannin St, MWT 1010, Houston, TX 77030 (e-mail: dhleung@texaschildrens.org).
Heather Van Doren, Senior Medical Editor with Arbor Research Collaborative for Health, provided editorial assistance on this manuscript. The authors thank the children and their families whose participation made this study possible.
D.H.L. reports grant/research support from Abbvie, Gilead, and CF Foundation; he also serves on advisory panels for Merck and Gilead. B.M.K. is a consultant for Mirum, Albireo and Audentes; she has unrestricted educational grants from Mirum and Albireo. V.L.N. is a consultant for Albireo. P.R. reports grants from Gilead, Merck, BMS, AbbVie, Travere Therapeutics, Albireo, and Mirum, Arrowhead; and serving as a consultant for Gilead, Mirum, Albireo, Audentes, and Vertex. R.J.S. reports consulting for Albireo, Mirum/Shire, and Retrophin (all <$10,000 per year). K.M.L. reports consulting for Albireo, Mirum and Retrophin (now known as Travere Therapeutics). The remaining authors report no conflicts of interest. The study sponsors did not have a role in study design; collection, analysis, and interpretation of data; writing of the report; or the decision to submit the paper for publication. Dr Heubi passed away on August 4, 2021, prior to publication of this article.
This work was supported by funding from the Alpha-1 Foundation (University of Colorado Denver and Saint Louis University School of Medicine) and by U01 grants from the National Institute of Diabetes, Digestive and Kidney Diseases and UL1 grants from the National Center for Advancing Translational Sciences (NCATS): DK062445 [Mt. Sinai School of Medicine], DK062497 and UL1 TR000077 [Cincinnati Children's Hospital Medical Center, University of Cincinnati], DK103149 [Texas Children's Hospital], DK062470 [Children's Healthcare of Atlanta, Emory University], DK062481 and UL1 TR000003 [The Children's Hospital of Philadelphia, University of Pennsylvania], DK062456 [University of Michigan], DK084536 and UL1 TR000006 [Riley Hospital for Children, Indiana University], DK084575 and UL1 TR000423 [Seattle Children's Hospital, University of Washington], DK062500 and UL1 TR000004 [UCSF Children's Hospital, University of California San Francisco], DK062503 and UL1 TR000424 [Johns Hopkins School of Medicine], DK062466 and UL1 TR000005 [Children's Hospital of Pittsburgh, University of Pittsburgh], DK062453 and UL1 TR002535 [University of Colorado Denver, Children's Hospital Colorado], DK062452 and UL1 TR000448 [Washington University School of Medicine, St. Louis, St. Louis Children's Hospital], DK084538 and UL1 TR000130 [Children's Hospital Los Angeles, University of Southern California], DK062436 and UL1 TR000150 [Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University], DK103140 [University of Utah], DK103135 [Hospital for Sick Children (Toronto)].
© 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition