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R.E, Email: eskandar@musc.edu
S.T, Email: tomlinss@musc.edu
M.A., K.M., A.A., S.T. and R.E. designed research; M.A., K.M., T.V., D.B. and C.C. performed research; M.A., K.M., T.V., C.S. and J.C. contributed unpublished reagents/analytic tools; M.A., K.M., T.V., J.C., C.S., R.E. and S.T. analyzed and interpreted data; M.A., K.M., J.C., S.T. and R.E. wrote the paper. All authors have read and agreed to the published version of the manuscript.
We acknowledge the MUSC Cell and Molecular Imaging Core, which is supported in part by the Cell & Molecular Imaging Shared Resource, MUSC Cancer Center Support Grant (P30 CA138313), the SC COBRE in Oxidants, Redox Balance, and Stress Signaling (P20 GM103542), the SC COBRE in Digestive and Liver Diseases (P20 GM130457), the MUSC Digestive Disease Core Center (P30 DK123704), and the Shared Instrumentation Grants S10 OD018113 and S10 OD028663.
S.T. is an inventor of a licensed patent for CR2-targeted complement inhibitors. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
This work was supported by the Neurosurgery Research and Education Foundation (NREF) through the AANS/CNS Section on Pediatric Neurological Surgery & NREF 2020-21 Research Fellowship Grant to MA. It was also supported by grants from the Department of Veterans Affairs (IK6BX005235, 1BX004256, 1RX001141) to ST, and the National Institutes of Health (NIH) (T32AI132164) to KM.
© 2022 by the authors.