About this item:

35 Views | 11 Downloads

Author Notes:

Soumitri Sil, Emory University School of Medicine, Children’s Health care of Atlanta, 2015 Uppergate Dr, Rm 426H, Atlanta, GA, USA. Email: soumitri.sil@emory.edu

This study was supported by the National Center for Advancing Translational Sciences (NCATS) of the NIH under Award UL1TR000454 and NHLBI Award 1K23Hl133457-01A1 to Soumitri Sil.

Kerri E. Woodward, Yelena L. Johnson, Lindsey L. Cohen, and Soumitri Sil have no conflicts of interest to report. Carlton Dampier has research funding from Pfizer, Micelle BioPharma, Novartis, Merck, Katz Foundation, and NIH/NICHD/NCATS; he is a consultant for Pfizer, Novartis, Global Blood Therapeutics, Epizyme, Micelle BioPharma, Modus Therapeutics, Hilton Publishing Company, and Ironwood Pharmaceutics; and he is on the advisory board of Pfizer, Novartis, and Micelle BioPharma.


Research Funding:

National Center for Advancing Translational Sciences (NCATS), NIH, Award Number: UL1TR000454; NHLBI, Award Number: 1K23Hl133457-01A1


  • Science & Technology
  • Life Sciences & Biomedicine
  • Oncology
  • Hematology
  • Pediatrics
  • health care utilization
  • pain
  • pediatrics
  • psychosocial risk
  • sickle cell disease
  • LIFE
  • PAIN

Psychosocial risk and health care utilization in pediatric sickle cell disease


Journal Title:



Volume 68, Number 8


, Pages e29139-e29139

Type of Work:

Article | Post-print: After Peer Review


Introduction: Pain and complications related to pediatric sickle cell disease (SCD) are associated with higher health care utilization. In other pediatric chronic conditions, psychosocial screening can help identify children and families at risk of increased health care utilization to guide resource allocation, address treatment needs, and improve care. This study aimed to investigate the utility of psychosocial screening in predicting increased health care utilization among youth with SCD. Methods: Youth with SCD (n = 74, 8–18 years) and their parents were recruited from comprehensive SCD clinics. Parents completed the Psychosocial Assessment Tool (PAT), which categorized family psychosocial risk into one of three categories: Universal (minimal distress), Targeted (elevated distress), and Clinical (persistent distress). Youth reported on their pain characteristics, and health care utilization was extracted from medical chart review. Differences in health care utilization were evaluated using analysis of variance (ANOVA) and moderation analyses. Results: Based on PAT risk, families were categorized into Universal (56.8%), Targeted (29.7%), and Clinical (13.5%) risk groups, with no significant group differences across demographic variables. Patients in the Targeted group reported significantly higher pain frequency than those in the Universal group (F[2, 66] = 3.7, p <.05). The association between pain frequency and health care utilization significantly varied on the basis of psychosocial risk, such that Clinical psychosocial risk strengthened the connection between pain frequency and health care utilization (β =.2, t = 2.1, p <.05). Conclusions: Integrating the PAT into routine clinical care may help health care providers identify families in need of greater psychosocial or medical support to further optimize SCD management.
Export to EndNote