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Author Notes:

Francisco J. Pasquel, MD, MPH, Department of Medicine, Emory University School of Medicine, 69 Jesse Hill Jr Dr SE, Atlanta, GA 30303 Email: fpasque@emory.edu

Mr Booth had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Concept and design: Pasquel, Messler, Booth, Kubacka, Umpierrez, Aloi. Acquisition, analysis, or interpretation of data: Pasquel, Messler, Booth, Mumpower, Aloi. Drafting of the manuscript: Pasquel, Booth, Kubacka, Mumpower. Critical revision of the manuscript for important intellectual content: Pasquel, Messler, Booth, Umpierrez, Aloi. Statistical analysis: Pasquel, Booth, Mumpower. Administrative, technical, or material support: Messler, Booth, Mumpower. Supervision: Pasquel, Messler, Aloi.

Dr Pasquel reported receiving research support from Dexcom and Merck and personal fees from Boehringer Ingelheim, AstraZeneca, Eli Lilly and Co, and Merck outside the submitted work. Dr Umpierrez reported receiving grants from Novo Nordisk, AstraZeneca, and Dexcom outside the submitted work. Dr Messler, Mr Booth, and Ms Kubacka reported working at Glytec at the time of the writing of this article. No other disclosures were reported.

Subject:

Research Funding:

Dr Pasquel is partially supported by the National Institutes of Health under award numbers 1K23GM128221-01A3 and P30DK111024-05S1.

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Medicine, General & Internal
  • General & Internal Medicine
  • TRENDS

Characteristics of and Mortality Associated With Diabetic Ketoacidosis Among US Patients Hospitalized With or Without COVID-19

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Journal Title:

JAMA NETWORK OPEN

Volume:

Volume 4, Number 3

Publisher:

, Pages e211091-e211091

Type of Work:

Article | Final Publisher PDF

Abstract:

Diabetic ketoacidosis (DKA) is a life-threatening, acute complication of diabetes. Despite an increase in DKA hospitalization rates, the age-adjusted DKA in-hospital case-fatality rate has declined over time.1 However, with the advent of coronavirus disease 2019 (COVID-19), a suspected increase in the frequency and severity of DKA has been hypothesized because of the potential diabetogenic effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).2 To further characterize patients with DKA with and without COVID-19, we analyzed individual-level inpatient data from multiple US hospitals.

Copyright information:

2021 Pasquel FJ et al. JAMA Network Open.

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/rdf).
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