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Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Obstetrics & Gynecology
  • Pediatrics
  • Neonate
  • Sepsis
  • Preterm
  • Bacteremia
  • Bacterial meningitis
  • Necrotizing enterocolitis neurodevelopment
  • Cerebral palsy
  • LOW-BIRTH-WEIGHT
  • LATE-ONSET SEPSIS
  • NECROTIZING ENTEROCOLITIS
  • PRETERM INFANTS
  • BACTERIAL-MENINGITIS
  • PREMATURE-INFANTS
  • CEREBRAL-PALSY
  • UNITED-STATES
  • IMPAIRMENT
  • IMPACT

Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome

Tools:

Journal Title:

CLINICS IN PERINATOLOGY

Volume:

Volume 48, Number 2

Publisher:

, Pages 251-261

Type of Work:

Article

Abstract:

Perinatal and neonatal infection and associated inflammatory response may adversely affect brain development and lead to neurodevelopmental impairment. Factors that predict the risk of infection and subsequent adverse outcomes have been identified but substantial gaps remain in identifying mechanisms and interventions that can alter outcomes. This article describes the current epidemiology of neonatal sepsis, the pathogenesis of brain injury with sepsis, and the reported long-term neurodevelopment outcomes among survivors.
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