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Author Notes:

Daniel S. Wechsler: dan.wechsler@emory.edu

This work was performed as part of the authors' employment by Children's Healthcare of Atlanta, Atlanta, GA

The authors have no conflicts of interest to disclose relevant to this article.


Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient.


Journal Title:

Case Rep Pediatr


Volume 2020


, Pages 8841607-8841607

Type of Work:

Article | Final Publisher PDF


Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as an unusual presentation of acute parvovirus B19 infection in a previously splenectomized 12-year-old boy with sickle cell disease.

Copyright information:

© 2020 Pratik A. Patel et al.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
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