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Angel Barco, Instituto de Neurociencias (Universidad Miguel Hernández – Consejo Superior de Investigaciones Científicas), Av Santiago Ramón y Cajal s/n, Sant Joan d’Alacant 03550, Alicante, Spain. Tel: +34 965 919232. abarco@umh.es
Conceptualization, J.F-A. and A.B.; Methodology, J.F-A., and A.B.; Software, J.F-A., and Formal analysis, J.F-A., M.J.R., and M.T.L-C.; Investigation, J.F-A., M.L., and A.M.M-G.; Data Curation and Visualization, J.F-A., M.T.L-C.; Resources, B.dB.; Writing – Original Draft, A.B. and J.F-A.; Supervision, A.B. and V.G.C.; Funding Acquisition, A.B. and V.G.C.
We thank Eloisa Herrera, Jose P. Lopez-Atalaya and Yijun Ruan for critical reading of the manuscript, and Román Olivares, Nuria Cascales, Antonio Caler and the personnel of the sequencing facility at the CRG (Barcelona, Spain) and HudsonAlpha (Alabama, USA) for technical assistance.
The authors do not express any conflict of interest.
JF-A and MTL-C are recipients of fellowships from the Spanish Ministry of Science and Innovation (MICINN). AB research is supported by grants SAF2017–87928-R and SEV-2017–0723 from MICINN co-financed by ERDF, PROM ETEO/2016/026 from the Generalitat Valenciana, and RGP0039/2017 from the Human Frontiers Science Program Organization (HFSPO). MJR is supported by the NIH Pathway to Independence Award K99/R00 GM127671.VGC research is supported by the U.S. Public Health Service Award (R01) GM035463 from the NIH. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The Instituto de Neurociencias is a “Centre of Excellence Severo Ochoa”.