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M.A.R. and E.A.E. performed in vitro experiments and analyzed in vitro data. S.A.L. performed computational simulations and analysis with guidance from J.A.W. L.B.W. guided and performed multivariate gene expression data analysis with M.A.R. M.A.R., L.K., J.A.W., J.D.B., R.E.G., and N.J.W. designed the experiments. All authors edited and approved the final manuscript.
We wish to acknowledge the core facilities at the Parker H. Petit Institute for Bioengineering and Bioscience at the Georgia Institute of Technology for the use of their shared equipment, services, and expertise.
The authors declare that they have no competing interests.
This work was supported by funding from the NIH (grant R01 AR069297). This material is the result of work supported with resources and the use of facilities at the Atlanta VA Medical Center along with funding from the VA (grant 5 I01 RX001985); the contents do not represent the views of the U.S. Department of Veterans Affairs or the U.S. government.
© 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works