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Correspondence: Richard D. Cummings, rcummin1@bidmc.harvard.edu
Author contributions: R.D.C. and J.Z. conceived and designed the project. J.Z. performed all experiments except for glycan release and analysis, which was conducted by S.L., IgG glycopeptide analysis by K.S., chemokine receptor biochemical analysis by R.P.A., and IVM by M.E. and U.H.v.A. J.W., Y.W., and T.J. generated the floxed Cosmc mice.
J.Z., K.S., S.L., M.E., and R.P.A. analyzed and interpreted the data with the assistance of M.R.K. R.D.C., R.P.A., and J.Z. wrote the manuscript, which was edited and approved by all authors.
The authors thank Dr. Michael Reth and Dr. John Manis for providing Mb1-Cre mice. We thank the BIDMC Histology, Confocal Microscopy, and Flow cytometry Core facility staff for their assistance.
We thank Dr. Jamie Heimburg-Molinaro for help in manuscript editing and review; members of the Cummings lab and Mark B. Jones for helpful discussions. We thank Dr. Rodrigo J. Gonzalez for help in video editing.
Disclosures: The authors declare no competing interests.
This work was supported by the HMS Center for Immune Imaging, and National Institute of Health Grant U01CA168930 to T.J. and R.D.C.
© The Author(s) 2020.