About this item:

143 Views | 148 Downloads

Author Notes:

Christine L. Moe, Email: clmoe@sph.emory.edu

The authors are grateful to Mr. Owen Herzegh for manuscript assistance and Ms. Melissa Dowd for statistical assistance.

Subject:

Research Funding:

The calicivirus research from Dr. Linda Saif’s lab, and discussed in this chapter, was supported by grant #R01-AI49742 from the NIAID, National Institutes of Health.

Dr. Juan Leon was supported by a postdoctoral fellowship in immunology (Human Immunology Award) from the Irvington Institute for Immunological Research and the Dana Foundation.

We are also grateful to the Emory General Clinical Research Center (GCRC) and their NIH National Center for Research Resources grant number M01 RR00039 for their support of our Emory norovirus human challenge study

Keywords:

  • Norwalk Virus
  • Histo Blood Group Antigen
  • Lamina Propia
  • STAT1 Knockout Mouse
  • Infected Volunteer

Immunology of Norovirus Infection

Tools:

Book Title:

Immunity Against Mucosal Pathogens

Publisher:

Publication Date:

Type of Work:

Chapter | Final Publisher PDF

Abstract:

Noroviruses are the leading cause of epidemic non-bacterial gastroenteritis worldwide. Despite their discovery over three decades ago, little is known about the host immune response to norovirus infection. The purpose of this chapter is to review the field of norovirus immunology and discuss the contributions of outbreak investigations, human and animal challenge studies and population-based studies. This chapter will survey both humoral and cellular immunity as well as recent advances in norovirus vaccine development.

Copyright information:

© Springer Science+Business Media B.V. 2008

This is an Open Access work distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
Export to EndNote