122 Views | 170 Downloads
Correspondence: Inyeong Choi, ichoi@emory.edu
I.C. led the project and wrote the manuscript. I.C. also performed alcohol-drinking behavior experiments.
J.R.S. and S.L. analyzed and interpreted data and edited the manuscript. C.E.G. performed electrophysiological recordings.
S.E.N., H.D.F., and J.C. (Emory) performed alcohol-related behavior experiments. J.M.L. performed perfusion/fxation.
Y.K. measured pH. L.A.J generated chronically alcohol-fed mice. J.C (UGA) and J.-K.L. collected brains from alcohol-fed and control mice. Z.J. performed qPCR in human brains.
C.A. and E.B. provided knockout mice. E.B. performed immunohistochemistry. All authors contributed to data analysis and interpretation.
The authors thank Dr. Michael Koval for providing brains of alcohol-fed and pair-fed mice, and Dr. Bryndis Birnir (Uppsala University, Sweden) for qPCR in post-mortem human brain tissues.
The authors also thank Jane H. Roenn (Aarhus University, Denmark) for expert technical assistance and Jason Lin for editing the manuscript.
The authors declare no competing interests.
Te work was supported by the National Institute of Health Pathway to Independence Award [AA021805] and the University of Georgia (J.R.S.) and by the NIH [GM078502-S], Emory University Research Committee and American Heart Association [14GRNT20480379] (I.C.).
© The Author(s) 2020.