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Correspondence; Jianhua Ran: ranjianhua@cqmu.edu.cn
Baoxue Yang: Baoxue@bjmu.edu.cn
Hongkai Wang, Boyue Huang, and Weiling Wang contributed equally to this work.
Hongkai Wang: Conceptualization, Data curation, Formal analysis, Writing - original draft.
Boyue Huang: Formal analysis, Writing - review & editing.
Weiling Wang: Data curation.
Jinfang Li: . Yi Chen: . Trevor Flynn: Data curation, Formal analysis.
Meng Zhao: . Zhiming Zhou: . Xiaojing Lin: . Yinan Zhang: . Mengmeng Xu: . Keqiong Li: Data curation.
Kuan Tian: . Dezhi Yuan: . Peng Zhou: . Ling Hu: . Dandan Zhong: . Shuai Zhu: . Jing Li: . Dilong Chen: . Kejian Wang: . Jianhui Liang: . Qihua He: . Jianbin Sun: . Jie Shi: . Li Yan: Data curation.
Jeff M Sands: . Zhengwei Xie: . Xuemei Lian: . Duan Xu: . Jianhua Ran: Conceptualization, Funding acquisition, Supervision, Writing - review & editing.
Baoxue Yang: Conceptualization, Funding acquisition, Supervision, Writing - review & editing.
The authors would like to thank Dr. Daqi Yu from School of Physics, Tianyu Zhang from School of Life Sciences, Bing Cao from School of Public Health, Peking University, Jingwei Song from Department of Statistics, University of California Los Angeles for enlightening conversation; Jingjie Li from Xi'an Jiaotong University, Junkui Shang from Capital Medical University, Chenyu Zhang and senior technician Mrs. Wenyuan Guo from School of Basic Medical Sciences, Peking University, Beian Dong and Yujiao Dou from Ion Channel Explorer Bioscience INC., Dr. Xingyu Zhang and Dr. Qiang Liu from the First People's Hospital of Chongqing Liang Jiang New Area for technologic assistance.
The authors declare no competing interests.
Funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript and eventually in the decision to submit the manuscript.
This work was supported by NIH R01HD072074, National Natural Science Foundation of China grants 81770738, 81620108029 and 81330074, International Science & Technology Cooperation Program of China grant 2012DFA11070, the 111 Project, the Scientific and Technological Research Program of Chongqing Yuzhongqu Scientific and Technological Commission (20120202), Research Program of Chongqing National Health and Family Planning Commission (2012-1-038), and the Chongqing Science and Technology Commission (Project No. cstc2015jcyjA10036).
© 2019 The Authors