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Author Notes:

Correspondence: May D. Wang, maywang@bme.gatech.edu

Acknowledgment: We appreciate Dr. Mitchell Parry, Todd Stokes, and Richard Moffitt from BioMIBLab for extensive discussions and preparation for this manuscript.

Subjects:

Research Funding:

This research has been supported by grants from National Institutes of Health (Bioengineering Research Partnership R01CA108468, P20GM072069, Center for Cancer Nanotechnology Excellence U54CA119338), Georgia Cancer Coalition (Distinguished Cancer Scholar Award to MDW), Hewlett Packard, and Microsoft Research.

Keywords:

  • gastroesophageal reflux disease
  • GERD
  • gastric acid flow
  • stomach
  • esophagus
  • lower esophageal sphincter
  • pathologic reflux
  • infant
  • surgical procedure
  • fundoplication
  • laproscopic surgical techniques

Development of a High Resolution 3D Infant Stomach Model for Surgical Planning

Tools:

Journal Title:

International Conference on Computer Analysis of Images and Patterns

Volume:

Volume 5702

Publisher:

, Pages 614-621

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Gastroesophageal reflux disease (GERD) is caused by gastric acid flowing from the stomach into the esophagus. Under healthy conditions, a physiologic barrier called the lower esophageal sphincter (LES) prevents pathologic reflux of stomach contents into the esophagus. GERD is an extremely common disease, affecting between 60 and 70 million people in the United States [2]. Chronic and extreme cases of GERD in infants can cause failure to thrive and damage the esophagus. When medical management fails, a surgical procedure called a fundoplication is performed. The most common fundoplication is the Nissen fundoplication, in which the fundus of the stomach is wrapped around the lower esophagus 360 degrees. This procedure is often performed using laparoscopic (minimally-invasive) surgical techniques. The procedure is not perfect and there is a recurrence rate of 10-15%, especially in infants. The surgeons at Emory Children's Hospital would like to improve the long-term results [2] of fundoplication using low risk system for testing first. We have formed an interdisciplinary team to design such system to meet the medical needs.

Copyright information:

© Springer-Verlag Berlin Heidelberg 2009

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