Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics

• Authors: Adolfo Ramirez-Zamora, University of Florida; James Giordano, Georgetown University; Edward S. Boyden, Massachusetts Institute of Technology; Viviana Gradinaru, California Institute of Technology; Aysegul Gunduz, University of Florida; Philip A. Starr, University of California, San Francisco; Sameer A. Sheth, Baylor College of Medicine; Cameron C. McIntyre, Case Western Reserve University; Michael D. Fox, Harvard Medical School; Jerrold Vitek, University of Minnesota; Vinata Vedam-Mai, University of Florida; Umer Akbar, Brown University; Leonardo Almeida, University of Florida; Helen M. Bronte-Stewart, Stanford University; Helen S Mayberg, Emory University; Nader Pouratian, University of California, Los Angeles; Aryn H. Gittis, Carnegie Mellon University; Annabelle Singer, Emory University; Meaghan C. Creed, University of Maryland
• Journal Title: Frontiers in Neuroscience
• Volume: Volume 13
• Publisher: Frontiers Media | 2019-09-12, Pages 936-936
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.3389/fnins.2019.00936
• Subjects: Biology, Neuroscience; Engineering, Biomedical
• Keywords: Science & Technology; Life Sciences & Biomedicine; Neurosciences; Neurosciences & Neurology; deep brain stimulation; neuromodulation; epilepsy; Parkinson's disease; tremor; optogenetics; Tourette syndrome; temporal dispersion; SUBTHALAMIC NUCLEUS STIMULATION; PARKINSONS-DISEASE; COORDINATED RESET; GLOBUS-PALLIDUS; THALAMIC SEGMENTATION; BETA-OSCILLATIONS; STN-DBS; GAIT; TRACTOGRAPHY; FREQUENCY

Abstract

The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The proceedings of the Sixth Annual Think Tank recapitulate progress in applications of neurotechnology, neurophysiology, and emerging techniques for the treatment of a range of psychiatric and neurological conditions including Parkinson’s disease, essential tremor, Tourette syndrome, epilepsy, cognitive disorders, and addiction. Each section of this overview provides insight about the understanding of neuromodulation for specific disease and discusses current challenges and future directions. This year’s report addresses key issues in implementing advanced neurophysiological techniques, evolving use of novel modulation techniques to deliver DBS, ans improved neuroimaging techniques. The proceedings also offer insights into the new era of brain network neuromodulation and connectomic DBS to define and target dysfunctional brain networks. The proceedings also focused on innovations in applications and understanding of adaptive DBS (closed-loop systems), the use and applications of optogenetics in the field of neurostimulation and the need to develop databases for DBS indications. Finally, updates on neuroethical, legal, social, and policy issues relevant to DBS research are discussed.