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Author Notes:
Paul A. Wade: wadep2@niehs.nih.gov
A.Y. Lai and M. Fatemi contributed equally to this paper.
We gratefully acknowledge the members of the Wade, Archer, and Adelman laboratories for many useful discussions and comments in the course of this work. This manuscript was substantially improved by critical comments from Trevor Archer, Tom Eling, and Harriet Kinyamu. We also thank Drs. Jeff Tucker, Daniel Gilchrist, Scott Norton, Kevin Gerrish, and the National Institute of Environmental Health Sciences microarray facility for their assistance in MIRA-chip experiments.
The authors have no conflicting financial interests.
Subjects:
Research Funding:
This work was supported by the Intramural Research Program of the National Institute of Environmental Health Sciences, National Institutes of Health (Project number Z01ES101965 to P.A. Wade, Project number Z01ES101765 to L. Li) and by grants from the National Institutes of Health (DK60647 to D.L. Jaye). D. Mav and R. Shah were supported in whole or in part with Federal funds from the National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, under Delivery Order Number HHSN291200555547C, GSA Contract Number GS-00F-003L.
Keywords:
- Science & Technology
- Life Sciences & Biomedicine
- Immunology
- Medicine, Research & Experimental
- Research & Experimental Medicine
- ENHANCER-BLOCKING ACTIVITY
- GENE-EXPRESSION
- HUMAN GENOME
- TRANSCRIPTIONAL REPRESSOR
- MAMMALIAN DEVELOPMENT
- DOWN-REGULATION
- UP-REGULATION
- X-CHROMOSOME
- PROTEIN CTCF
- CANCER-CELLS
DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
Abstract:
Copyright information:
© 2010 by the Rockefeller University Press
