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Tracey J Lamb, Division of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine and Emory Children's Centre, 2015 Uppergate Drive, Atlanta, Georgia 30322, USA. Telephone: +1-404-712-7883; Fax number: +1-404-727-9223; tracey.j.lamb@emory.edu.
PNM conceived the design of the experiments, performed the experiments, analyzed the data and wrote the manuscript; LMB, CFB, MT, CDM, TPK, SM, KQ and CL performed the experiments; EM and AG contributed reagents and intellectual input; TJL conceived the design of the experiments, analyzed the data and wrote the manuscript.
We thank Professor Jonathan Gibbins, University of Reading, UK for providing EphB2−/− animals; and the staff of the Division of Animal Resources for excellent animal husbandry.
We also thank Mr Aaron Rae of the Emory Pediatric Flow Cytometry Core for cell sorting; Miss Katie Casper in the Emory Pediatric Immunology Core for assistance with qPCR analysis and primers designed; Miss Deborah E. Martison and Mr Neil Anthony in the Emory University Integrated Cellular Imaging Core for assistance with microscopy.
Authors had no conflicts of interest to disclose.
TJL is supported by National Institute for Neurological Disorders and Strokes (1R21NS085382-01A1); Children's Healthcare of Atlanta; the Royal Societ;y and Emory Egleston Children's Research Centre.
MT is supported by the NRSA training grant T32 (2T32AI70081-06AI, FY2013-2014) and F32 Fellowship grant (1F32DK101163-01, FY2014-2015).
AG is supported in part by EVC/CFAR Immunology Core P30 AI050409; Yerkes Research Center Base Grant RR-0016;, and Public Health Service AI070101.
© 2015 by the American Association for the Study of Liver Diseases.