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E-mail address: rahmed@emory.edu; virgin@wustl.edu; karaki@emory.edu
X.X., K.A., S.L., M.W.B., J.M., D.R.G., D.P.J., H.W.V. and R.A. designed the research; X.X., K.A., S.L., J.-H.H., L.Y., W.G.T. and B.T.K. performed experiments.
X.X., K.A., S.L., M.W.B., E.L.P., D.R.G., D.P.J., H.W.V. and R.A. analyzed data; and X.X., K.A., S.L., E.L.P., H.W.V. and R.A. wrote the manuscript.
We thank A. Rao (La Jolla Institute for Allergy and Immunology) for the MSCV-IRES-Thy-1.1 retroviral vector; J. Jacob (Emory University) for Gzmb-Cre transgenic mice; V. Tran for the LC-MS experiments; R. Karaffa and S. Durham for sorting cells by flow cytometry at the Emory Flow Cytometry Core Facility; and A. Rae for assistance in the use of ImageStream.
The authors declare no competing financial interests.
Supported by the US National Institutes of Health (R01 AI030048 to R.A. and R01 AI084887 to H.W.V.), the Mérieux Foundation (R.A.) and the Crohn's and Colitis Foundation (H.W.V.).