Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium

• Authors: Belinda Rivera-Lebron, University of Pittsburgh; Michael McDaniel, Emory University; Kamran Ahrar, University of Texas MD Anderson Cancer Center; Abdulah Alrifai, University of Miami; David M. Dudzinski, Harvard Medical School; Christina Fanola, University of Minnesota; Danielle Blais, Ohio State University; David Janicke, University of Buffalo; Roman Melamed, Abbott Northwestern Hospital; Kerry Mohrien, Temple University; Elizabeth Rozycki, Ohio State University; Charles B. Ross, Piedmont Heart Institute; Andrew J. Klein, Piedmont Heart Institute; Parth Rali, Temple University; Nicholas R. Teman, University of Virginia; Leoara Yarboro, University of Virginia; Eugene Ichinose, Oklahoma Heart Institute; Aditya M. Sharma, University of Virginia; Jason A. Bartos, University of Minnesota; Mahir Elder, Wayne State University; Brent Keeling, Emory University; Harold Palevsky, University of Pennsylvania; Soophia Naydenov, St Louis University; Parijat Sen, Henry Ford Hospital; Nancy Amoroso, New York University; Josanna M. Rodriguez-Lopez, Harvard Medical School; George A. Davis, University of Kentucky; Rachel Rosovsky, Harvard Medical School; Kenneth Rosenfield, Harvard Medical School; Christopher Kabrhel, Harvard Medical School; James Horowitz, New York University; Jay S. Giri, University of Pennsylvania; Victor Tapson, Cedars Sinai Medical Center; Richard Channick, University of California Los Angeles
• Journal Title: Clinical and Applied Thrombosis/Hemostasis
• Volume: Volume 25
• Publisher: SAGE Publications (UK and US): Open Access Titles | 2019-06-10, Pages 1076029619853037-1076029619853037
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.1177/1076029619853037
• Subjects: Health Sciences, Medicine and Surgery
• Keywords: Science & Technology; Life Sciences & Biomedicine; Hematology; Peripheral Vascular Disease; Cardiovascular System & Cardiology; acute pulmonary embolism; venous thromboembolism; pulmonary embolism response team; systemic thrombolysis; catheter-directed thrombolysis; embolectomy; inferior vena cava filter; chronic thromboembolic pulmonary hypertension; EXTRACORPOREAL MEMBRANE-OXYGENATION; RIGHT HEART THROMBI; CATHETER-DIRECTED THROMBOLYSIS; ULTRASOUND-ACCELERATED THROMBOLYSIS; TISSUE-PLASMINOGEN-ACTIVATOR; SIMPLE CLINICAL-MODEL; CARDIAC-ARREST; RANDOMIZED-TRIAL; RESPONSE TEAM; CARDIOPULMONARY-RESUSCITATION

Abstract

Pulmonary embolism (PE) is a life-threatening condition and a leading cause of morbidity and mortality. There have been many advances in the field of PE in the last few years, requiring a careful assessment of their impact on patient care. However, variations in recommendations by different clinical guidelines, as well as lack of robust clinical trials, make clinical decisions challenging. The Pulmonary Embolism Response Team Consortium is an international association created to advance the diagnosis, treatment, and outcomes of patients with PE. In this consensus practice document, we provide a comprehensive review of the diagnosis, treatment, and follow-up of acute PE, including both clinical data and consensus opinion to provide guidance for clinicians caring for these patients.