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Author Notes:
Correspondence: Chuan He, Department of Chemistry and Institute for Biophysical Dynamics, University of Chicago, Chicago, Illinois 60637; Email: chuanhe@uchicago.edu
or Jing Chen, Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322; Email: jchen@emory.edu
Authors' Contributions: The first two authors contributed equally to this work.
Acknowledgments: We thank Susan Sunay at the Hematology Division Tissue Bank, Winship Cancer Institute of Emory for providing primary tissue samples from leukemia patients, Drs. Sagar Lonial and Lawrence Boise for providing peripheral blood samples from healthy donors, and Dr. Yoke Wah Kow for human HaCaT and PIG1 cell lines.
Disclosures: J.X. and T.-L.G. are employees of Cell Signaling Technology, Inc.
T.H. is a Fellow Scholar of the American Society of Hematology.
S. E. is an NIH pre-doctoral fellow and an ARCS Foundation Scholar.
G.Z.C., D.M.S., F.R.K., S.K. and J.C. are Georgia Cancer Coalition Distinguished Cancer Scholars.
S. K. is a Robbins Scholar.
S.K. and J.C. are American Cancer Society Basic Research Scholars.
J.C. is a Scholar of the Leukemia and Lymphoma Society.
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Research Funding:
This work was supported in part by NIH grants CA120272 (J.C.), CA140515 (J.C.), GM071440 (C.H.) and the Pharmacological Sciences Training Grant T32 GM008602 (S.E.).
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth
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© 2012 Elsevier Inc. All rights reserved.
