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Correspondence: rmburke@emory.edu

RMB developed the study objectives, contributed data entry, completed data cleaning and analysis, and drafted the manuscript.

ERS contributed to the design of survey instruments.

ERS, MRD, and PAR participated in data entry, preliminary data analysis, and contributed to the drafting of the manuscript.

MCC, BC, EC, RP, LT, CT, and RZ contributed to study design, oversight of field work, and drafting of the manuscript.

VI contributed to study design, protocol, survey instruments, and contributed to the drafting of the manuscript.

JSL oversaw the development of study objectives, protocol, survey instruments, data analysis, and manuscript drafting.

The final version of the manuscript has been read and approved by RMB, ERS, MRD, PAR, BC, EC, RP, LT, CT, RZ, VI, and JSL.

MCC passed away prior to the finalization of the manuscript.

We are grateful for the support of the hospital staff and the many study participants involved in this study.

The contents of this paper are solely the responsibility of the authors and do not necessarily represent the official views of the USDA or the National Institutes of Health.

The authors declare that they have no competing interests.

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Research Funding:

This work was supported in part by The Eugene J. Gangarosa Fund; the Anne E. and William A. Foege Global Health Fund; the O.C. Hubert Charitable Trust; the RSPH Student Initiative Fund; the NIH Global Frameworks Grant (2007–2010); the Emory University Global Health Institute; the Laney Graduate School at Emory University; the New Aid Fellowship; the Bolivia National Rotavirus Surveillance Program (BNRSP); the Swedish Cooperation ASDI-UMSA (Diarrhea Disease Project); PHS Grant UL1 TR000454 from the Clinical and Translational Science Award Program, National Institutes of Health, National Center for Research Resource; the Emory + Children’s Pediatric Center Seed Grant Program; The National Institutes of Health/NIAID grant U19-AI057266; and the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR000454.

RMB was supported in part by an NIH T32 training grant in reproductive, pediatric, and perinatal epidemiology (HD052460-01).

PAR was supported by the National Institute of Allergy and Infectious Diseases (Award number T32AI074492).

JSL was supported in part by funds from the Emory University Global Health Institute, NIH-NIAID (1K01AI087724-01) and USDA-NIFA (2010-85212-20608) grants.

Keywords:

  • Pediatric gastroenteritis
  • Diarrhea
  • Societal costs
  • Health economics

The economic burden of pediatric gastroenteritis to Bolivian families: a cross-sectional study of correlates of catastrophic cost and overall cost burden

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BMC Public Health

Volume:

Volume 14, Number 642

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Type of Work:

Article | Final Publisher PDF

Abstract:

Background Worldwide, acute gastroenteritis causes substantial morbidity and mortality in children less than five years of age. In Bolivia, which has one of the lower GDPs in South America, 16% of child deaths can be attributed to diarrhea, and the costs associated with diarrhea can weigh heavily on patient families. To address this need, the study goal was to identify predictors of cost burden (diarrhea-related costs incurred as a percentage of annual income) and catastrophic cost (cost burden ≥ 1% of annual household income). Methods From 2007 to 2009, researchers interviewed caregivers (n = 1,107) of pediatric patients (<5 years old) seeking treatment for diarrhea in six Bolivian hospitals. Caregivers were surveyed on demographics, clinical symptoms, direct (e.g. medication, consult fees), and indirect (e.g. lost wages) costs. Multivariate regression models (n = 551) were used to assess relationships of covariates to the outcomes of cost burden (linear model) and catastrophic cost (logistic model). Results We determined that cost burden and catastrophic cost shared the same significant (p < 0.05) predictors. In the logistic model that also controlled for child sex, child age, household size, rural residence, transportations taken to the current visit, whether the child presented with complications, and whether this was the child’s first episode of diarrhea, significant predictors of catastrophic cost included outpatient status (OR 0.16, 95% CI [0.07, 0.37]); seeking care at a private hospital (OR 4.12, 95% CI [2.30, 7.41]); having previously sought treatment for this diarrheal episode (OR 3.92, 95% CI [1.64, 9.35]); and the number of days the child had diarrhea prior to the current visit (OR 1.14, 95% CI [1.05, 1.24]). Conclusions Our analysis highlights the economic impact of pediatric diarrhea from the familial perspective and provides insight into potential areas of intervention to reduce associated economic burden.

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© 2014 Burke et al.; licensee BioMed Central Ltd.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 2.0 Generic License (http://creativecommons.org/licenses/by/2.0/).

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