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Author Notes:

Correspondence: Edward Faught, M.D., Emory Epilepsy Program, Department of Neurology A3100, 1365 Clifton Road NE, Atlanta, GA 30322. E-mail: rfaught@emory.edu

Subject:

Ezogabine: A New Angle On Potassium Gates

Tools:

Journal Title:

Epilepsy Currents

Volume:

Volume 11, Number 3

Publisher:

, Pages 75-78

Type of Work:

Article | Final Publisher PDF

Abstract:

Ezogabine is a new drug for adjunctive therapy of partial-onset seizures with a novel mechanism of action. As a potassium-channel facilitator, it promotes membrane repolarization and thus opposes rapid repetitive discharges. Side effects are typical for antiepileptic drugs and the safety profile is good. Occasional instances of urinary difficulty may require surveillance.

Copyright information:

© American Epilepsy Society

This is an Open Access work distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/).

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