Neurological Principles and Rehabilitation of Action Disorders: Common Clinical Deficits

• Authors: Krishnankutty Sathian, Emory University; Laurel J. Buxbaum, Moss Rehabilitation Research Institute; Leonardo G. Cohen, National Institutes of Health; John W. Krakauer, Johns Hopkins University; Catherine E. Lang, Washington University in St. Louis; Maurizio Corbetta, Washington University in St. Louis; Susan M. Fitzpatrick, James S. McDonnell Foundation
• Journal Title: Neurorehabilitation and Neural Repair
• Volume: Volume 25, Number 5 Suppl
• Publisher: SAGE Publications (UK and US) | 2011-06-01, Pages 21S-32S
• Type of Work: Article | Post-print: After Peer Review
• Publisher DOI: http://doi.org/10.1177/1545968311410941
• Subjects: Biology, Neuroscience; Psychology, Cognitive
• Keywords: Science & Technology; Life Sciences & Biomedicine; Clinical Neurology; Rehabilitation; Neurosciences & Neurology; NATURALISTIC ACTION; MOVEMENT CONTROL; STROKE; RECOVERY; APRAXIA; CEREBELLUM; LESIONS; HAND

Abstract

In this chapter, the authors use the computation, anatomy, and physiology (CAP) principles to consider the impact of common clinical problems on action. They focus on 3 major syndromes: paresis, apraxia, and ataxia. They also review mechanisms that could account for spontaneous recovery, using what is known about the best-studied clinical dysfunction—paresis—and also ataxia. Together, this and the previous chapter lay the groundwork for the third chapter in this series, which reviews the relevant rehabilitative interventions.