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A.M.K. (email: anna.kenney@emory.edu)
V.M., D.H. and A.M.K. contributed to conception, design of the study and methodology; V.M., Z.C., C.J.H., Y.W., N.S.S. and M.H.R. acquired, analysed and interpreted the data; V.M., V.A.R. and P.A.N. analysed the human patient data; V.M., Z.C., D.H. and A.M.K. wrote the paper; K.C.G. and T.J.M. provided additional material support and comments; All authors read the manuscript and approved the final version.
We thank the Pathology Core Laboratory of Winship Cancer Institute for paraffin embedding of tissues and whole-slide scanning; Children’s Healthcare of Atlanta and Emory Pediatrics Flow Cytometry Core for help with flow cytometry; as well as Neil Anthony and Emory Integrated Cellular Imaging Core for help with images acquisition and analysis.
We thank Dmitry Shayakhmetov and Nelson Di Paolo for help with BMDM cultures and productive discussions.
We would like to thank Robert Wechsler-Reya and Alexandra Garancher for providing MB group 3 mouse model cells.
The authors declare no competing interests.
This work was supported by: R01-NS061070 (A.M.K.); U01-CA160882 (D.H.); R01-NS100864 (D.H.); NCI Winship Cancer Institute P30 Centre Grant CA138292; 1F31NS106887 (C.J.H.); Sontag Foundation (P.A.N.); V Foundation (P.A.N.) and American Lebanese Syrian Associated Charities (P.A.N.).
© 2019, The Author(s).