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Author Notes:

Correspondence: Andrew S Neish; aneish@emory.edu

Disclosures: The authors declare that they have no competing interests.


Research Funding:

The laboratory of ASN is supported by the National Institutes of Health (DK71604 and AI64462).

Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses


Journal Title:

F1000 Biology Reports


Volume 2, Number 27


Type of Work:

Article | Final Publisher PDF


Commensal gut bacteria are necessary for the complete development of mucosal innate and adaptive immunity and thus may influence intestinal and systemic immune disorders. Recent work has advanced our understanding of this association by identification of a single taxon of the murine microbiota which can stimulate T-cell development and differentiation. It is hoped that further characterization of the mechanisms involved will enable targeted manipulation of the microbiota-immune system relationship.

Copyright information:

© 2010 Faculty of 1000 Ltd

This is an Open Access work distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/).

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