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Author Notes:

Correspondence: sanchezn@mskcc.org 1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Authors’ contributions: NFS participated in patient recruitment, statistical analysis, and manuscript preparation.

BS participated in patient recruitment, data entry and analysis as well as manuscript preparation.

SS participated in patient recruitment and manuscript preparation.

DM participated in patient recruitment, data entry, and manuscript preparation.

HY participated in patient recruitment and manuscript preparation.

FF participated in the design of the study, patient recruitment, sample procurement, statistical analysis, and manuscript preparation.

All authors read and approved the final manuscript.

Competing interests: The authors declare that they have no competing interests.

Subjects:

Research Funding:

Supported in part by grant 1UL1RR029893 from the National Center for Research Resources, National Institutes of Health, and the Michael Saperstein Medical Scholars Program. We thank the NYU School of Medicine Office of Diversity Affairs, the Division of Gastroenterology, its fellows, and nurses for their support.

Keywords:

  • Adenoma
  • African Americans
  • Age Factors
  • Asian Americans
  • Chi-Square Distribution
  • Colonic Polyps
  • Colonoscopy
  • Colorectal Neoplasms
  • Ethnic Groups
  • European Continental Ancestry Group
  • Exercise
  • Female
  • Hispanic Americans
  • Humans
  • Logistic Models
  • Male
  • Mass Screening
  • Middle Aged
  • Multivariate Analysis
  • New York City
  • Obesity
  • Odds Ratio
  • Overweight
  • Prevalence
  • Prospective Studies
  • Risk Assessment
  • Risk Factors
  • Risk Reduction Behavior
  • Sex Factors
  • Urban Health

Physical activity reduces risk for colon polyps in a multiethnic colorectal cancer screening population

Tools:

Journal Title:

BMC Research Notes

Volume:

Volume 5, Number 1

Publisher:

, Pages 312-312

Type of Work:

Article | Final Publisher PDF

Abstract:

Background: Identifying modifiable factors that influence the epidemiology of colorectal cancer incidence among multiethnic groups might be informative for the development of public health strategies targeting the disease. Minimal data exists describing the impact of physical activity on colorectal polyp risk in United States minority populations. The aim of this study is to evaluate the relationship of exercise on the prevalence of polyps in a multiethnic colorectal cancer screening population. Results: We enrolled 982 patients: 558 Hispanic, 202 Asian,149 Black, and 69 White. Patients who reported exercising one or more hours weekly had a lower prevalence of any polyps (25.3% vs 33.2%, P = 0.008) as well as adenomas (13.8 vs. 18.9%, P = 0.03) compared to those who did not exercise. Black and Hispanic patients and those who were overweight or obese also had lower prevalence of polyps if they led an active lifestyle. Multivariate analysis revealed that age >55, male sex, and Black race/ethnicity were positively associated with the presence of adenomas, while a history of exercising one hour or more weekly was an independent negative predictor for the presence of adenomas anywhere in the colon (OR 0.67; 95% CI 0.4 - 0.9, P = 0.03). Conclusions: Exercising one hour per week was associated with a lower prevalence of polyps and adenomas when compared to those who exercised less or not at all. An active lifestyle provides benefits to groups who are at risk for colorectal cancer, such as Blacks. It also provides significant protection to overweight and obese individuals. Public health initiatives should promote physical activity as a cancer prevention tool in multiethnic populations.

Copyright information:

© 2012 Sanchez et al.; licensee BioMed Central Ltd.

This is an Open Access work distributed under the terms of the Creative Commons Attribution-NoDerivs 2.0 Generic License (http://creativecommons.org/licenses/by-nd/2.0/).

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