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Author Notes:

Correspondence concerning this article should be addressed to Michael J Morrier, Emory Autism Center, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1551 Shoup Court, Decatur, GA 30033. michael.j.morrier@emory.edu; Phone number: 404.727.8350; Fax number: 404.727.3969

We thank Catherine Rice, Nikolaou Loizos, Lauren Castriota and Nichole Evans for their assistance.


Research Funding:

This research was supported in part by the Silvio O Conte Center for Oxytocin and Social Cognition from the National Institute of Mental Health 1P50MH1000023.


  • Social Sciences
  • Psychology, Developmental
  • Psychology
  • Calibrated severity scores
  • ADOS-2
  • Module 4
  • Verbal intellectual quotient
  • SRS-2
  • AQ
  • SCL-90

Brief Report: Relationship Between ADOS-2, Module 4 Calibrated Severity Scores (CSS) and Social and Non-Social Standardized Assessment Measures in Adult Males with Autism Spectrum Disorder (ASD)


Journal Title:

Journal of Autism and Developmental Disorders


Volume 47, Number 12


, Pages 4018-4024

Type of Work:

Article | Post-print: After Peer Review


The ADOS-2 Modules 1–3 now include a standardized calibrated severity score (CSS) from 1 to 10 based on the overall total raw score. Subsequent research published CSS for Module 4 (Hus, Lord, Journal of Autism and Developmental Disorders 44(8):1996–2012, 2014); however more research is needed to examine the psychometric properties of this CSS. Forty males with ASD completed an assessment battery consisting of ADOS-2 Module 4 and other clinical measures assessing core ASD symptomology and comorbidity. Pearson correlation analyses found that CSS did not correlate with measures that assessed core social deficits of ASD or general psychiatric co-morbidity, but CSS did correlate negatively with intellectual quotient. These findings provide information on the limitations and relevance of CSS to be taken into account in future clinical evaluations of ASD.

Copyright information:

© 2017, Springer Science+Business Media, LLC.

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