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Correspondence and requests for materials should be addressed to J.H. (email: huj@ibp.ac.cn) or to J.-T.D. (email: j.dong@emory.edu) or to Z.Z. (email: zhuzhengmao@nankai.edu.cn)
Z.Z., J.T.D., and J.H. conceived and designed the study.
A.G., T.S., and G.M. performed cell culture experiments, histology, immunohistochemistry, and analysis.
A.G. and J.C. performed Mouse xenograft studies.
Z.Z. and L.C. contributed tissue array experiments and recording data analysis.
Z.Z. and Y.W. performed Kaplan–Meier analysis.
A.G. and Q.W. performed cell cycle analysis.
Q.H., T.S., Q.W., and J.S. contributed the GST-pulldown and IP and results.
A.G. and R.W. contributed CHX chase assay and results.
J.Z., L.L., J.T.D. provided comments on the manuscript.
Z.Z., J.H., and A.G. contributed manuscript preparation.
The authors thank Drs. Yushan Zhu and Jun Zhou for providing plasmids and materials.
The authors thank Dr Tao Zhu for providing MCF7-TAMR cell model.
The authors declare no competing interests.
The study was supported by the National Natural Science Foundation of China (Grant No. 91649107 and 81402320), the Natural Science Foundation of Tianjin City of China (Grant No. 17JCYBJC24100 and 16JCYBJC27000), and the Strategic Priority Research Program (Pilot study) “Biological basis of aging and therapeutic strategies” of the Chinese Academy of Sciences (grant XDPB10).
© 2018, The Author(s).