About this item:

80 Views | 99 Downloads

Author Notes:

Corresponding author: Rupak Desai, drrupakdesai@gmail.com

The content published in Cureus is the result of clinical experience and/or research by independent individuals or organizations.

Cureus is not responsible for the scientific accuracy or reliability of data or conclusions published herein.

All content published within Cureus is intended only for educational, research and reference purposes.

Additionally, articles published within Cureus should not be deemed a suitable substitute for the advice of a qualified health care professional.

Do not disregard or avoid professional medical advice due to content published within Cureus.

The authors have declared that no competing interests exist.

Consent was obtained by all participants in this study.

All authors have confirmed that this study did not involve animal subjects or tissue.



  • all-cause mortality
  • calcified lesions
  • cardiovascular complications
  • coronary atherectomy
  • coronary atherosclerosis
  • hospitalization cost
  • hypothyroidism
  • outcomes
  • pci
  • percutaneous coronary intervention

Impact of Hypothyroidism on Outcomes of Percutaneous Coronary Intervention with Coronary Atherectomy for Calcified Coronary Lesions: A Propensity-matched Analysis.


Journal Title:



Volume 10, Number 5


, Pages e2600-e2600

Type of Work:

Article | Final Publisher PDF


Overt and subclinical hypothyroid states have been depicted as risk factors for a more prominent level of coronary calcification. The utilization of coronary atherectomy with percutaneous coronary intervention (PCI) is on the ascent over the past few years as lesions that are more complex are now attempted with a percutaneous approach. However, the real-world data on hypothyroid status influencing PCI with coronary atherectomy outcomes is very limited. Therefore, we proposed to investigate the outcomes of percutaneous coronary intervention with coronary atherectomy in hypothyroid patients using the largest inpatient database in the United States (US), the National Inpatient Sample (NIS). To minimize the selection bias, we surveyed and compared the outcomes in both the unmatched and propensity-score matched euthyroid and hypothyroid cohorts. Concisely, this propensity-matched analysis, using the largest population-based sample in the US, has established higher cardiovascular comorbidities and worse clinical outcomes of PCI with coronary atherectomy owing to clinical hypothyroidism.

Copyright information:

© 2018, Desai et al.

This is an Open Access work distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/).

Creative Commons License

Export to EndNote