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Author Notes:

Corresponding Author: Esi M. Morgan, MD, Cincinnati Children’s Hospital Medical Center, Division of Rheumatology, 3333 Burnet Avenue, MLC 4010. Cincinnati Ohio 45229, telephone: (513) 636-4676, fax: (513) 636-4116; esi.morgan_dewitt@cchmc.org; https:// www.cincinnatichildrens.org/.

We are indebted to C. Jeffrey Jacobson, PhD for his extensive contributions to the qualitative work that underlay development of the Pain Behavior item bank.

This project would not have been possible without the excellent research assistance from Jennifer Farrell, Kimberly Barnett, Jenna Tress, Leann Schilling, and Caravella McCuistian for assistance with patient recruiting, administration of questionnaires and regulatory compliance.

We are grateful to the patients and parent participants in this research study.

There are no conflicts of interest for the study authors.

Subjects:

Research Funding:

The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring PROs in respondents with a wide range of chronic diseases and demographic characteristics.

PROMIS II was funded by cooperative agreements with a Statistical Center (Northwestern University, PI: David Cella, PhD, 1U54AR057951), a Technology Center (Northwestern University, PI: Richard C. Gershon, PhD, 1U54AR057943), a Network Center (American Institutes for Research, PI: Susan (San) D. Keller, PhD, 1U54AR057926) and thirteen Primary Research Sites which may include more than one institution (State University of New York, Stony Brook, PIs: Joan E. Broderick, PhD and Arthur A. Stone, PhD, 1U01AR057948; University of Washington, Seattle, PIs: Heidi M. Crane, MD, MPH, Paul K. Crane, MD, MPH, and Donald L. Patrick, PhD, 1U01AR057954; University of Washington, Seattle, PIs: Dagmar Amtmann, PhD and Karon Cook, PhD, 1U01AR052171; University of North Carolina, Chapel Hill, PI: Darren A. DeWalt, MD, MPH, 2U01AR052181; Children’s Hospital of Philadelphia, PI: Christopher B. Forrest, MD, PhD, 1U01AR057956; Stanford University, PI: James F. Fries, MD, 2U01AR052158; Boston University, PIs: Stephen M. Haley, PhD and David Scott Tulsky, PhD (University of Michigan, Ann Arbor), 1U01AR057929; University of California, Los Angeles, PIs: Dinesh Khanna, MD and Brennan Spiegel, MD, MSHS, 1U01AR057936; University of Pittsburgh, PI: Paul A. Pilkonis, PhD, 2U01AR052155; Georgetown University, PIs: Carol. M. Moinpour, PhD (Fred Hutchinson Cancer Research Center, Seattle) and Arnold L. Potosky, PhD, U01AR057971; Children’s Hospital Medical Center, Cincinnati, PI: Esi M. Morgan DeWitt, MD, MSCE, 17 1U01AR057940; University of Maryland, Baltimore, PI: Lisa M. Shulman, MD, 1U01AR057967; and Duke University, PI: Kevin P. Weinfurt, PhD, 2U01AR052186).

NIH Science Officers on this project have included Deborah Ader, PhD, Vanessa Ameen, MD, Susan Czajkowski, PhD, Basil Eldadah, MD, PhD, Lawrence Fine, MD, DrPH, Lawrence Fox, MD, PhD, Lynne Haverkos, MD, MPH, Thomas Hilton, PhD, Laura Lee Johnson, PhD, Michael Kozak, PhD, Peter Lyster, PhD, Donald Mattison, MD, Claudia Moy, PhD, Louis Quatrano, PhD, Bryce Reeve, PhD, William Riley, PhD, Ashley Wilder Smith, PhD, MPH, Susana Serrate-Sztein, MD, Ellen Werner, PhD and James Witter, MD, PhD.

Keywords:

  • Science & Technology
  • Life Sciences & Biomedicine
  • Anesthesiology
  • Clinical Neurology
  • Neurosciences
  • Neurosciences & Neurology
  • Pediatric pain
  • Pain behavior
  • Item response theory
  • Patient-reported outcomes
  • Juvenile fibromyalgia
  • Juvenile arthritis
  • Sickle cell disease
  • PROMIS
  • LOW-BACK-PAIN
  • PSYCHOMETRIC PROPERTIES
  • RESPONSE THEORY
  • CHILDREN
  • ADOLESCENTS
  • HEALTH
  • PARENT
  • DISABILITY
  • IMPACT
  • CANDIDATES

Development and validation of the self-reported PROMIS pediatric pain behavior item bank and short form scale

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Journal Title:

PAIN

Volume:

Volume 158, Number 7

Publisher:

, Pages 1323-1331

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Pain behaviors are important indicators of functioning in chronic pain; however, no self-reported pain behavior instrument has been developed for pediatric populations. The purpose of this study was to create a brief pediatric measure of patient-reported pain behaviors as part of the Patient-Reported Outcome Measurement Information System (PROMIS). A pool of 47 candidate items for this measure had been previously developed through qualitative research. In this study, youth with chronic pain associated with juvenile fibromyalgia, juvenile idiopathic arthritis, or sickle cell disease (ages 8-18 years) from 3 pediatric centers completed all 47 candidate items for development of the pain behavior item bank along with established measures of pain interference, depressive symptoms, fatigue, average pain intensity, and pain catastrophizing. Caregivers reported on sociodemographic information and health history. Psychometric properties of the pain behavior items were examined using an item response theory framework with confirmatory factor analysis and examination of differential item functioning, internal consistency, and test information curves. Results were used along with expert consensus and alignment with the adult PROMIS pain behavior items to arrive at an 8-item pediatric pain behavior short form, and all 47 items were retained in a calibrated item bank. Confirmatory factor analysis and correlations with validated measures of pain, pain interference, and psychosocial functioning provided support for the short form's reliability and validity. The new PROMIS pediatric pain behavior scale provides a reliable, precise, and valid measure for future research on pain behavior in school-aged children with chronic pain.

Copyright information:

© 2017 International Association for the Study of Pain.

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