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Author Notes:

E-mail Address : vin.tangpricha@emory.edu E-mail Address : tzieg01@emory.edu E-mail Address : greg.martin@emory.edu

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Research Funding:

This work was supported in part by National Institutes of Health grants T32 AA013528 (JAK), R21 HL110044, K23AR054334 (VT), K24 RR023356 (TRZ), U54 RR-024380, and P50 AA-013757 (GSM) and the Atlanta Clinical and Translational Science Institute (UL1 RR025008).

Vitamin D in sepsis: from basic science to clinical impact

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Journal Title:

Critical Care

Volume:

Volume 16, Number 4

Publisher:

, Pages 316-316

Type of Work:

Article | Final Publisher PDF

Abstract:

The growing basic and clinical investigations into the extraskeletal effects of vitamin D have revealed roles in the functioning of the immune system, generating interesting questions about this nutrient's connections to sepsis. This article briefly reviews the current science of the function of vitamin D in the immune system as well as the emerging clinical literature regarding its associations with respiratory infections, sepsis, and critical illness. Finally, we offer views on the potential future directions for research in the field by outlining potential relevant scenarios and outcomes.

Copyright information:

© 2012 BioMed Central Ltd

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