Covarying ionic conductances to emulate phase maintenance in stomatogastric neurons

• Authors: Wafa Soofi, Emory University; Astrid A Prinz, Emory University
• Journal Title: BMC Neurology
• Volume: Volume 11, Number Suppl 1
• Publisher: BioMed Central | 2010-07-20, Pages P60-P60
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.1186/1471-2202-11-S1-P60
• Subjects: Biology, General; Engineering, Biomedical

Abstract

Neuronal networks produce reliable functional output throughout the lifespan of an animal despite ceaseless molecular turnover and a constantly changing environment. Central pattern generators, such as that of the crustacean stomatogastric ganglion (STG), robustly maintain their functionality over a wide range of burst periods [1]. Extracellular recordings of the LP neuron of the STG have demonstrated that as the burst period varies over time, the interspike intervals change proportionally, so that the spike phases are relatively invariant.