In Vivo Ocular Fluorophotometry: Delivery of Fluoresceinated Dextrans via Transscleral Diffusion in Rabbits

• Authors: Damian E. Berezovsky, Emory University; Samirkumar R. Patel, Georgia Institute of Technology; Bernard E McCarey, Emory University; Henry Edelhauser, Emory University
• Journal Title: Investigative Ophthalmology & Visual Science
• Volume: Volume 52, Number 10
• Publisher: Association for Research in Vision and Ophthalmology, Inc. | 2011-09, Pages 7038-7045
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.1167/iovs.11-7207
• Subjects: Health Sciences, Medicine and Surgery

Abstract

Fluoresceinated dextrans up to 70 kDa in size were delivered to the rabbit posterior retina and choroid using sub-Tenon injections. Intraocular fluorescence was monitored in vivo with noninvasive ocular fluorophotometry.