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Author Notes:

Address correspondence to Sarah W. Satola, ssatola@emory.edu.

We thank Priscilla Maldonado-Estrada, Henry K. Lowery, and the Atlanta VAMC clinical microbiology laboratory for their assistance in specimen collection and handling.

We have no potential conflicts of interest to declare.


Research Funding:

This study was supported by CDC Interagency Agreement 07FED706507 and PHS grant UL RR025008 from the Clinical and Translational Science Award program, National Institutes of Health, National Center for Research Resources.

Cepheid Xpert MRSA Cycle Threshold in Discordant Colonization Results and as a Quantitative Measure of Nasal Colonization Burden


Journal Title:

Journal of Clinical Microbiology


Volume 50, Number 6


, Pages 2079-2081

Type of Work:

Article | Final Publisher PDF


We analyzed the cycle threshold (CT) of PCR surveillance MRSA swabs obtained from veterans. Lower CT on admission was associated with a positive culture from nasal swabs at discharge. Compared to PCR, direct plating of nasal swabs performed poorly, especially for patients with an elevated CT. The CT is strongly correlated with quantitative nasal cultures. Clinical and infection control applications of the CT have yet to be defined and warrant further evaluation.

Copyright information:

© 2012, American Society for Microbiology. All Rights Reserved.

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