Particle therapy for non-small cell lung tumors: Where do we stand? A systematic review of the literature

• Authors: Krista C. J. Wink, Maastricht University; Erik Roelofs, Maastricht University; Timothy Solberg, University of Pennsylvania; Liyong Lin, Emory University; Charles B. Simone, University of Pennsylvania; Annika Jakobi, OncoRay - National Center for Radiation Research in Oncology; Christian Richter, OncoRay - National Center for Radiation Research in Oncology; Philippe Lambin, Maastricht University; Esther G. C. Troost, Maastricht University
• Journal Title: Frontiers in Oncology
• Volume: Volume 4, Number OCT
• Publisher: Frontiers Media | 2014-01-01, Pages 292-292
• Type of Work: Article | Final Publisher PDF
• Publisher DOI: http://doi.org/10.3389/fonc.2014.00292
• Subjects: Health Sciences, Oncology; Health Sciences, General
• Keywords: C-ion; IMPT; NSCLC; PBS; PSPT; photon; proton; radiotherapy

Abstract

This review article provides a systematic overview of the currently available evidence on the clinical effectiveness of particle therapy for the treatment of NSCLC and summarizes findings of in silico comparative planning studies. Furthermore, technical issues and dosimetric uncertainties with respect to thoracic pa rticle therapy are discussed.