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Author Notes:

Correspondence: Emmy K. Bell (ekbell@uab.edu).

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Neurological Disorders and Stroke or the National Institutes of Health.

Representatives of the funding agency have been involved in the review of the manuscript but not directly involved in the collection, management, analysis or interpretation of the data.

The authors thank the other investigators, the staff, and the participants of the REGARDS study for their valuable contributions.

A full list of participating REGARDS investigators and institutions can be found at http://www.regardsstudy.org.

Amgen did not have any role in the design and conduct of the study, the collection, management, data analysis, or interpretation of the data, or the preparation or approval of the manuscript.

L.G. had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Amgen did not have any role in the design and conduct of the study, the collection, management, data analysis, or interpretation of the data, or the preparation or approval of the manuscript.

Disclosure: The authors declared no conflict of interest.

Subjects:

Research Funding:

This research project is supported by a cooperative agreement U01 NS041588 from the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Service.

Additional funding was provided by an investigator-initiated grant-in-aid from Amgen Corporation to D.G.W.

Keywords:

  • Blood Pressure
  • Chronic Kidney Disease
  • End-Stage Renal Disease
  • Hypertension
  • Pulse Pressure
  • Systolic Blood Pressure

Blood Pressure Indexes and End-Stage Renal Disease Risk in Adults With Chronic Kidney Disease

Tools:

Journal Title:

American Journal of Hypertension

Volume:

Volume 25, Number 7

Publisher:

, Pages 789-796

Type of Work:

Article | Post-print: After Peer Review

Abstract:

Few studies have compared different blood pressure (BP) indexes for end-stage renal disease (ESRD) risk among individuals with chronic kidney disease.We examined the relationship between systolic BP (SBP), diastolic BP (DBP), pulse pressure (PP) and mean arterial pressure (MAP) and ESRD risk among 2,772 participants with an estimated glomerular filtration rate (eGFR) <60ml/min/1.73 m2 calculated using the Chronic Kidney Disease Epidemiology Collaboration equation in the REasons for the Geographic And Racial Differences in Stroke (REGARDS) study. BP was measured during a baseline study visit between January 2003 and October 2007 with ESRD incidence through August 2009 ascertained via linkage with the United States Renal Data System (n = 138 ESRD cases).

Copyright information:

© 2012 American Journal of Hypertension, Ltd.

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